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Unanchored K48-linked polyubiquitin synthesized by the E3-ubiquitin ligase TRIM6 stimulates the interferon-IKKε kinase-mediated antiviral response.
Rajsbaum R, Versteeg GA, Schmid S, Maestre AM, Belicha-Villanueva A, Martínez-Romero C, Patel JR, Morrison J, Pisanelli G, Miorin L, Laurent-Rolle M, Moulton HM, Stein DA, Fernandez-Sesma A, tenOever BR, García-Sastre A. Rajsbaum R, et al. Immunity. 2014 Jun 19;40(6):880-95. doi: 10.1016/j.immuni.2014.04.018. Epub 2014 May 29. Immunity. 2014. PMID: 24882218 Free PMC article.
Innate immune sensing of flaviviruses.
Suthar MS, Aguirre S, Fernandez-Sesma A. Suthar MS, et al. PLoS Pathog. 2013 Sep;9(9):e1003541. doi: 10.1371/journal.ppat.1003541. Epub 2013 Sep 12. PLoS Pathog. 2013. PMID: 24068919 Free PMC article. Review. No abstract available.
DENV inhibits type I IFN production in infected cells by cleaving human STING.
Aguirre S, Maestre AM, Pagni S, Patel JR, Savage T, Gutman D, Maringer K, Bernal-Rubio D, Shabman RS, Simon V, Rodriguez-Madoz JR, Mulder LC, Barber GN, Fernandez-Sesma A. Aguirre S, et al. PLoS Pathog. 2012;8(10):e1002934. doi: 10.1371/journal.ppat.1002934. Epub 2012 Oct 4. PLoS Pathog. 2012. PMID: 23055924 Free PMC article.
Innate immunity evasion by Dengue virus.
Morrison J, Aguirre S, Fernandez-Sesma A. Morrison J, et al. Viruses. 2012 Mar;4(3):397-413. doi: 10.3390/v4030397. Epub 2012 Mar 15. Viruses. 2012. PMID: 22590678 Free PMC article. Review.
11 results