Biotransformations of 1',2'-dihydrorotenone by Streptomyces griseus

Appl Environ Microbiol. 1985 Feb;49(2):451-2. doi: 10.1128/aem.49.2.451-452.1985.

Abstract

Dihydrorotenone yields three major products when incubated with growing cultures of Streptomyces griseus. These were isolated by solvent extraction and characterized by spectral methods as 1',2'-dihydro-6abeta-hydroxyrotenone, 1',2'-dihydro-2',6abeta-dihydroxyrotenone, and 1',2'-dihydro-1',6abeta-dihydroxyrotenone.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Biotransformation
  • Magnetic Resonance Spectroscopy
  • Rotenone / analogs & derivatives*
  • Rotenone / metabolism
  • Streptomyces griseus / metabolism*

Substances

  • Rotenone
  • 1',2'-dihydrorotenone
  • 1',2'-dihydro-2',6-dihydroxyrotenone
  • 1',2'-dihydro-1'-6-dihydroxyrotenone
  • 1',2'-dihydro-6-hydroxyrotenone