Phenethyl alcohol and tryptophol: autoantibiotics produced by the fungus Candida albicans

Science. 1969 Jan 10;163(3863):192-4. doi: 10.1126/science.163.3863.192.

Abstract

Two autoantibiotics produced by the fungus Candida albicans have been identified, with the aid of mass spectrometry, as 2-phenylethanol and 3-beta-hydroxyethylindole. The cyclodipeptides, cyclo(proline-leucine) and cyclo(proline-phenylalanine) were also isolated from cultures of Candida albicans, but did not inhibit the growth of the fungus.

MeSH terms

  • Anti-Bacterial Agents / biosynthesis*
  • Candida / metabolism*
  • Chromatography
  • Dipeptides / isolation & purification
  • Ethanol*
  • Indoles / biosynthesis*
  • Infrared Rays
  • Spectrum Analysis

Substances

  • Anti-Bacterial Agents
  • Dipeptides
  • Indoles
  • Ethanol