Blue Sclerae and Differential Diagnosis in Chest Pain: A Case Report

Luana C Miantti Ghellere Bonfim; Isadora S Guerini; Marjorie G Zambon; Marcela A Lopes

doi:10.7759/cureus.43542

Blue Sclerae and Differential Diagnosis in Chest Pain: A Case Report

Cureus. 2023 Aug 15;15(8):e43542. doi: 10.7759/cureus.43542. eCollection 2023 Aug.

Authors

Luana C Miantti Ghellere Bonfim¹, Isadora S Guerini², Marjorie G Zambon³, Marcela A Lopes⁴

Affiliations

¹ Department of Medicine, University of South Santa Catarina, Florianopolis, BRA.
² Department of Medicine, Western Parana State University, Francisco Beltrão, BRA.
³ Department of Medicine, Mackenzie Evangelical University Hospital, Curitiba, BRA.
⁴ Department of Critical Care, Hospital da Cidade, Salvador, BRA.

Abstract

Osteogenesis imperfecta (OI) constitutes a complex connective tissue disorder extending beyond its hallmark bone fragility. This case report explores the intricate diagnostic journey involving an elderly patient with acute chest pain, blue sclerae, and multiple fractures. Despite a thorough cardiac evaluation yielding normal results, the complex medical history and phenotypic markers directed attention toward musculoskeletal factors, underlining the importance of comprehensive diagnostic approaches in hereditary conditions like OI.

Keywords: blue sclerae; chest pain; connective tissue disorders; costochondritis; osteogenesis imperfecta; scoliosis; skeletal dysplasia.

Publication types

Case Reports