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The presence of the pAA plasmid in the German O104:H4 Shiga toxin type 2a (Stx2a)-producing enteroaggregative Escherichia coli strain promotes the translocation of Stx2a across an epithelial cell monolayer.
Boisen N, Hansen AM, Melton-Celsa AR, Zangari T, Mortensen NP, Kaper JB, O'Brien AD, Nataro JP. Boisen N, et al. J Infect Dis. 2014 Dec 15;210(12):1909-19. doi: 10.1093/infdis/jiu399. Epub 2014 Jul 18. J Infect Dis. 2014. PMID: 25038258 Free PMC article.
Origins of the E. coli strain causing an outbreak of hemolytic-uremic syndrome in Germany.
Rasko DA, Webster DR, Sahl JW, Bashir A, Boisen N, Scheutz F, Paxinos EE, Sebra R, Chin CS, Iliopoulos D, Klammer A, Peluso P, Lee L, Kislyuk AO, Bullard J, Kasarskis A, Wang S, Eid J, Rank D, Redman JC, Steyert SR, Frimodt-Møller J, Struve C, Petersen AM, Krogfelt KA, Nataro JP, Schadt EE, Waldor MK. Rasko DA, et al. N Engl J Med. 2011 Aug 25;365(8):709-17. doi: 10.1056/NEJMoa1106920. Epub 2011 Jul 27. N Engl J Med. 2011. PMID: 21793740 Free PMC article.