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SIV vpx is essential for macrophage infection but not for development of AIDS.
Westmoreland SV, Converse AP, Hrecka K, Hurley M, Knight H, Piatak M, Lifson J, Mansfield KG, Skowronski J, Desrosiers RC. Westmoreland SV, et al. PLoS One. 2014 Jan 21;9(1):e84463. doi: 10.1371/journal.pone.0084463. eCollection 2014. PLoS One. 2014. PMID: 24465411 Free PMC article.
Mechanism of allosteric activation of SAMHD1 by dGTP.
Ji X, Wu Y, Yan J, Mehrens J, Yang H, DeLucia M, Hao C, Gronenborn AM, Skowronski J, Ahn J, Xiong Y. Ji X, et al. Nat Struct Mol Biol. 2013 Nov;20(11):1304-9. doi: 10.1038/nsmb.2692. Epub 2013 Oct 20. Nat Struct Mol Biol. 2013. PMID: 24141705 Free PMC article.