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Early defects in translation elongation factor 1α levels at excitatory synapses in α-synucleinopathy.
Blumenstock S, Angelo MF, Peters F, Dorostkar MM, Ruf VC, Luckner M, Crux S, Slapakova L, Arzberger T, Claverol S, Herzog E, Herms J. Blumenstock S, et al. Acta Neuropathol. 2019 Dec;138(6):971-986. doi: 10.1007/s00401-019-02063-3. Epub 2019 Aug 26. Acta Neuropathol. 2019. PMID: 31451907
Using fluorescence-activated synaptosome sorting (FASS), we enriched excitatory glutamatergic synaptosomes from mice overexpressing human alpha-synuclein (h-alphaS) and wild-type littermates to unprecedented purity. Subsequent label-free proteomic quantification revealed a …
Using fluorescence-activated synaptosome sorting (FASS), we enriched excitatory glutamatergic synaptosomes from mice overexpressing human al …
Sequential alteration of microglia and astrocytes in the rat thalamus following spinal nerve ligation.
Blaszczyk L, Maître M, Lesté-Lasserre T, Clark S, Cota D, Oliet SHR, Fénelon VS. Blaszczyk L, et al. J Neuroinflammation. 2018 Dec 20;15(1):349. doi: 10.1186/s12974-018-1378-z. J Neuroinflammation. 2018. PMID: 30572902 Free PMC article.
We also studied by immunohistofluorescence the expression of glial markers that label processes (GFAP for astrocytes and iba-1 for microglia) and cell body (S100beta for astrocytes and iba-1 for microglia) and quantified the immunostained surface and the number of astrocyt …
We also studied by immunohistofluorescence the expression of glial markers that label processes (GFAP for astrocytes and iba-1 for mi …