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Tubular mitochondrial pyruvate carrier disruption elicits redox adaptations that protect from acute kidney injury.
Rauckhorst AJ, Vasquez Martinez G, Mayoral Andrade G, Wen H, Kim JY, Simoni A, Robles-Planells C, Mapuskar KA, Rastogi P, Steinbach EJ, McCormick ML, Allen BG, Pabla NS, Jackson AR, Coleman MC, Spitz DR, Taylor EB, Zepeda-Orozco D. Rauckhorst AJ, et al. Among authors: simoni a. Mol Metab. 2024 Jan;79:101849. doi: 10.1016/j.molmet.2023.101849. Epub 2023 Dec 7. Mol Metab. 2024. PMID: 38056691 Free PMC article.
Tubular Mitochondrial Pyruvate Carrier Disruption Elicits Redox Adaptations that Protect from Acute Kidney Injury.
Rauckhorst AJ, Martinez GV, Andrade GM, Wen H, Kim JY, Simoni A, Mapuskar KA, Rastogi P, Steinbach EJ, McCormick ML, Allen BG, Pabla NS, Jackson AR, Coleman MC, Spitz DR, Taylor EB, Zepeda-Orozco D. Rauckhorst AJ, et al. Among authors: simoni a. bioRxiv [Preprint]. 2023 Jan 31:2023.01.31.526492. doi: 10.1101/2023.01.31.526492. bioRxiv. 2023. PMID: 36778297 Free PMC article. Updated. Preprint.
Repurposing HDAC inhibitors to enhance ribonuclease 4 and 7 expression and reduce urinary tract infection.
Schwartz L, Bochter MS, Simoni A, Bender K, de Dios Ruiz Rosado J, Cotzomi-Ortega I, Sanchez-Zamora YI, Becknell B, Linn S, Li B, Santoro N, Eichler T, Spencer JD. Schwartz L, et al. Among authors: simoni a. Proc Natl Acad Sci U S A. 2023 Jan 24;120(4):e2213363120. doi: 10.1073/pnas.2213363120. Epub 2023 Jan 18. Proc Natl Acad Sci U S A. 2023. PMID: 36652479 Free PMC article.
Insulin receptor signaling engages bladder urothelial defenses that limit urinary tract infection.
Schwartz L, Salamon K, Simoni A, Eichler T, Jackson AR, Murtha M, Becknell B, Kauffman A, Linn-Peirano S, Holdsworth N, Tyagi V, Tang H, Rust S, Cortado H, Zabbarova I, Kanai A, Spencer JD. Schwartz L, et al. Among authors: simoni a. Cell Rep. 2024 Mar 21;43(4):114007. doi: 10.1016/j.celrep.2024.114007. Online ahead of print. Cell Rep. 2024. PMID: 38517889 Free article.