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2021 3
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Page 1
Itaconate confers tolerance to late NLRP3 inflammasome activation.
Bambouskova M, Potuckova L, Paulenda T, Kerndl M, Mogilenko DA, Lizotte K, Swain A, Hayes S, Sheldon RD, Kim H, Kapadnis U, Ellis AE, Isaguirre C, Burdess S, Laha A, Amarasinghe GK, Chubukov V, Roddy TP, Diamond MS, Jones RG, Simons DM, Artyomov MN. Bambouskova M, et al. Among authors: ellis ae. Cell Rep. 2021 Mar 9;34(10):108756. doi: 10.1016/j.celrep.2021.108756. Cell Rep. 2021. PMID: 33691097 Free PMC article.
NF1 deficiency drives metabolic reprogramming in ER+ breast cancer.
House RRJ, Tovar EA, Redlon LN, Essenburg CJ, Dischinger PS, Ellis AE, Beddows I, Sheldon RD, Lien EC, Graveel CR, Steensma MR. House RRJ, et al. Among authors: ellis ae. Mol Metab. 2024 Feb;80:101876. doi: 10.1016/j.molmet.2024.101876. Epub 2024 Jan 10. Mol Metab. 2024. PMID: 38216123 Free PMC article.
Structure of an AMPK complex in an inactive, ATP-bound state.
Yan Y, Mukherjee S, Harikumar KG, Strutzenberg TS, Zhou XE, Suino-Powell K, Xu TH, Sheldon RD, Lamp J, Brunzelle JS, Radziwon K, Ellis A, Novick SJ, Vega IE, Jones RG, Miller LJ, Xu HE, Griffin PR, Kossiakoff AA, Melcher K. Yan Y, et al. Among authors: ellis a. Science. 2021 Jul 23;373(6553):413-419. doi: 10.1126/science.abe7565. Science. 2021. PMID: 34437114 Free PMC article.
1-Methylnicotinamide is an immune regulatory metabolite in human ovarian cancer.
Kilgour MK, MacPherson S, Zacharias LG, Ellis AE, Sheldon RD, Liu EY, Keyes S, Pauly B, Carleton G, Allard B, Smazynski J, Williams KS, Watson PH, Stagg J, Nelson BH, DeBerardinis RJ, Jones RG, Hamilton PT, Lum JJ. Kilgour MK, et al. Among authors: ellis ae. Sci Adv. 2021 Jan 20;7(4):eabe1174. doi: 10.1126/sciadv.abe1174. Print 2021 Jan. Sci Adv. 2021. PMID: 33523930 Free PMC article.
Prior metabolite extraction fully preserves RNAseq quality and enables integrative multi-'omics analysis of the liver metabolic response to viral infection.
Madaj ZB, Dahabieh MS, Kamalumpundi V, Muhire B, Pettinga J, Siwicki RA, Ellis AE, Isaguirre C, Escobar Galvis ML, DeCamp L, Jones RG, Givan SA, Adams M, Sheldon RD. Madaj ZB, et al. Among authors: ellis ae. RNA Biol. 2023 Jan;20(1):186-197. doi: 10.1080/15476286.2023.2204586. RNA Biol. 2023. PMID: 37095747 Free PMC article.