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The HDAC3-SMARCA4-miR-27a axis promotes expression of the PAX3:FOXO1 fusion oncogene in rhabdomyosarcoma.
Bharathy N, Berlow NE, Wang E, Abraham J, Settelmeyer TP, Hooper JE, Svalina MN, Ishikawa Y, Zientek K, Bajwa Z, Goros MW, Hernandez BS, Wolff JE, Rudek MA, Xu L, Anders NM, Pal R, Harrold AP, Davies AM, Ashok A, Bushby D, Mancini M, Noakes C, Goodwin NC, Ordentlich P, Keck J, Hawkins DS, Rudzinski ER, Chatterjee B, Bächinger HP, Barr FG, Liddle J, Garcia BA, Mansoor A, Perkins TJ, Vakoc CR, Michalek JE, Keller C. Bharathy N, et al. Among authors: abraham j. Sci Signal. 2018 Nov 20;11(557):eaau7632. doi: 10.1126/scisignal.aau7632. Sci Signal. 2018. PMID: 30459282 Free PMC article.
Preclinical rationale for entinostat in embryonal rhabdomyosarcoma.
Bharathy N, Berlow NE, Wang E, Abraham J, Settelmeyer TP, Hooper JE, Svalina MN, Bajwa Z, Goros MW, Hernandez BS, Wolff JE, Pal R, Davies AM, Ashok A, Bushby D, Mancini M, Noakes C, Goodwin NC, Ordentlich P, Keck J, Hawkins DS, Rudzinski ER, Mansoor A, Perkins TJ, Vakoc CR, Michalek JE, Keller C. Bharathy N, et al. Among authors: abraham j. Skelet Muscle. 2019 May 21;9(1):12. doi: 10.1186/s13395-019-0198-x. Skelet Muscle. 2019. PMID: 31113472 Free PMC article.
An adaptive Src-PDGFRA-Raf axis in rhabdomyosarcoma.
Abraham J, Chua YX, Glover JM, Tyner JW, Loriaux MM, Kilcoyne A, Giles FJ, Nelon LD, Carew JS, Ouyang Y, Michalek JE, Pal R, Druker BJ, Rubin BP, Keller C. Abraham J, et al. Biochem Biophys Res Commun. 2012 Sep 28;426(3):363-8. doi: 10.1016/j.bbrc.2012.08.092. Epub 2012 Aug 30. Biochem Biophys Res Commun. 2012. PMID: 22960170 Free PMC article.
PDGFRβ reverses EphB4 signaling in alveolar rhabdomyosarcoma.
Aslam MI, Abraham J, Mansoor A, Druker BJ, Tyner JW, Keller C. Aslam MI, et al. Among authors: abraham j. Proc Natl Acad Sci U S A. 2014 Apr 29;111(17):6383-8. doi: 10.1073/pnas.1403608111. Epub 2014 Apr 14. Proc Natl Acad Sci U S A. 2014. PMID: 24733895 Free PMC article.
Lineage of origin in rhabdomyosarcoma informs pharmacological response.
Abraham J, Nuñez-Álvarez Y, Hettmer S, Carrió E, Chen HI, Nishijo K, Huang ET, Prajapati SI, Walker RL, Davis S, Rebeles J, Wiebush H, McCleish AT, Hampton ST, Bjornson CR, Brack AS, Wagers AJ, Rando TA, Capecchi MR, Marini FC, Ehler BR, Zarzabal LA, Goros MW, Michalek JE, Meltzer PS, Langenau DM, LeGallo RD, Mansoor A, Chen Y, Suelves M, Rubin BP, Keller C. Abraham J, et al. Genes Dev. 2014 Jul 15;28(14):1578-91. doi: 10.1101/gad.238733.114. Genes Dev. 2014. PMID: 25030697 Free PMC article.
Probabilistic modeling of personalized drug combinations from integrated chemical screen and molecular data in sarcoma.
Berlow NE, Rikhi R, Geltzeiler M, Abraham J, Svalina MN, Davis LE, Wise E, Mancini M, Noujaim J, Mansoor A, Quist MJ, Matlock KL, Goros MW, Hernandez BS, Doung YC, Thway K, Tsukahara T, Nishio J, Huang ET, Airhart S, Bult CJ, Gandour-Edwards R, Maki RG, Jones RL, Michalek JE, Milovancev M, Ghosh S, Pal R, Keller C. Berlow NE, et al. Among authors: abraham j. BMC Cancer. 2019 Jun 17;19(1):593. doi: 10.1186/s12885-019-5681-6. BMC Cancer. 2019. PMID: 31208434 Free PMC article.
IL-4R drives dedifferentiation, mitogenesis, and metastasis in rhabdomyosarcoma.
Hosoyama T, Aslam MI, Abraham J, Prajapati SI, Nishijo K, Michalek JE, Zarzabal LA, Nelon LD, Guttridge DC, Rubin BP, Keller C. Hosoyama T, et al. Among authors: abraham j. Clin Cancer Res. 2011 May 1;17(9):2757-66. doi: 10.1158/1078-0432.CCR-10-3445. Clin Cancer Res. 2011. PMID: 21536546 Free PMC article.
Dynamic and nuclear expression of PDGFRα and IGF-1R in alveolar Rhabdomyosarcoma.
Aslam MI, Hettmer S, Abraham J, Latocha D, Soundararajan A, Huang ET, Goros MW, Michalek JE, Wang S, Mansoor A, Druker BJ, Wagers AJ, Tyner JW, Keller C. Aslam MI, et al. Among authors: abraham j. Mol Cancer Res. 2013 Nov;11(11):1303-13. doi: 10.1158/1541-7786.MCR-12-0598. Epub 2013 Aug 8. Mol Cancer Res. 2013. PMID: 23928059 Free PMC article.
1,952 results