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Specific substitutions in the echinocandin target Fks1p account for reduced susceptibility of rare laboratory and clinical Candida sp. isolates.
Park S, Kelly R, Kahn JN, Robles J, Hsu MJ, Register E, Li W, Vyas V, Fan H, Abruzzo G, Flattery A, Gill C, Chrebet G, Parent SA, Kurtz M, Teppler H, Douglas CM, Perlin DS. Park S, et al. Among authors: abruzzo g. Antimicrob Agents Chemother. 2005 Aug;49(8):3264-73. doi: 10.1128/AAC.49.8.3264-3273.2005. Antimicrob Agents Chemother. 2005. PMID: 16048935 Free PMC article. Clinical Trial.
Efficacy of caspofungin in a juvenile mouse model of central nervous system candidiasis.
Flattery AM, Hickey E, Gill CJ, Powles MA, Misura AS, Galgoci AM, Ellis JD, Zhang R, Sandhu P, Ronan J, Abruzzo GK. Flattery AM, et al. Among authors: abruzzo gk. Antimicrob Agents Chemother. 2011 Jul;55(7):3491-7. doi: 10.1128/AAC.01328-10. Epub 2011 Apr 25. Antimicrob Agents Chemother. 2011. PMID: 21518846 Free PMC article.
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