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Supplementation with a prebiotic (polydextrose) in obese mouse pregnancy improves maternal glucose homeostasis and protects against offspring obesity.
Maragkoudaki X, Naylor M, Papacleovoulou G, Stolarczyk E, Rees D, Pombo JM, Abu-Hayyeh S, Czajka A, Howard JK, Malik AN, Williamson C, Poston L, Taylor PD. Maragkoudaki X, et al. Among authors: abu hayyeh s. Int J Obes (Lond). 2020 Dec;44(12):2382-2393. doi: 10.1038/s41366-020-00682-5. Epub 2020 Oct 8. Int J Obes (Lond). 2020. PMID: 33033395
Maternal cholestasis during pregnancy programs metabolic disease in offspring.
Papacleovoulou G, Abu-Hayyeh S, Nikolopoulou E, Briz O, Owen BM, Nikolova V, Ovadia C, Huang X, Vaarasmaki M, Baumann M, Jansen E, Albrecht C, Jarvelin MR, Marin JJ, Knisely AS, Williamson C. Papacleovoulou G, et al. Among authors: abu hayyeh s. J Clin Invest. 2013 Jul;123(7):3172-81. doi: 10.1172/JCI68927. Epub 2013 Jun 24. J Clin Invest. 2013. PMID: 23934127 Free PMC article.
Ursodeoxycholic acid improves feto-placental and offspring metabolic outcomes in hypercholanemic pregnancy.
Borges Manna L, Papacleovoulou G, Flaviani F, Pataia V, Qadri A, Abu-Hayyeh S, McIlvride S, Jansen E, Dixon P, Chambers J, Vazquez-Lopez M, Wahlström A, Kitaba N, Marschall HU, Godfrey KM, Lillycrop K, Williamson C. Borges Manna L, et al. Among authors: abu hayyeh s. Sci Rep. 2020 Jun 25;10(1):10361. doi: 10.1038/s41598-020-67301-1. Sci Rep. 2020. PMID: 32587408 Free PMC article.
A progesterone-brown fat axis is involved in regulating fetal growth.
McIlvride S, Mushtaq A, Papacleovoulou G, Hurling C, Steel J, Jansen E, Abu-Hayyeh S, Williamson C. McIlvride S, et al. Among authors: abu hayyeh s. Sci Rep. 2017 Sep 6;7(1):10671. doi: 10.1038/s41598-017-10979-7. Sci Rep. 2017. PMID: 28878263 Free PMC article.
Changes in LXR signaling influence early-pregnancy lipogenesis and protect against dysregulated fetoplacental lipid homeostasis.
Nikolova V, Papacleovoulou G, Bellafante E, Borges Manna L, Jansen E, Baron S, Abu-Hayyeh S, Parker M, Williamson C. Nikolova V, et al. Among authors: abu hayyeh s. Am J Physiol Endocrinol Metab. 2017 Oct 1;313(4):E463-E472. doi: 10.1152/ajpendo.00449.2016. Epub 2017 Apr 18. Am J Physiol Endocrinol Metab. 2017. PMID: 28420650 Free PMC article.
25 results