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Stable coordination of the inhibitory Ca2+ ion at the metal ion-dependent adhesion site in integrin CD11b/CD18 by an antibody-derived ligand aspartate: implications for integrin regulation and structure-based drug design.
Mahalingam B, Ajroud K, Alonso JL, Anand S, Adair BD, Horenstein AL, Malavasi F, Xiong JP, Arnaout MA. Mahalingam B, et al. Among authors: adair bd. J Immunol. 2011 Dec 15;187(12):6393-401. doi: 10.4049/jimmunol.1102394. Epub 2011 Nov 16. J Immunol. 2011. PMID: 22095715 Free PMC article.
Atomic basis for the species-specific inhibition of αV integrins by monoclonal antibody 17E6 is revealed by the crystal structure of αVβ3 ectodomain-17E6 Fab complex.
Mahalingam B, Van Agthoven JF, Xiong JP, Alonso JL, Adair BD, Rui X, Anand S, Mehrbod M, Mofrad MR, Burger C, Goodman SL, Arnaout MA. Mahalingam B, et al. Among authors: adair bd. J Biol Chem. 2014 May 16;289(20):13801-9. doi: 10.1074/jbc.M113.546929. Epub 2014 Apr 1. J Biol Chem. 2014. PMID: 24692540 Free PMC article.
uPAR isoform 2 forms a dimer and induces severe kidney disease in mice.
Wei C, Li J, Adair BD, Zhu K, Cai J, Merchant M, Samelko B, Liao Z, Koh KH, Tardi NJ, Dande RR, Liu S, Ma J, Dibartolo S, Hägele S, Peev V, Hayek SS, Cimbaluk DJ, Tracy M, Klein J, Sever S, Shattil SJ, Arnaout MA, Reiser J. Wei C, et al. Among authors: adair bd. J Clin Invest. 2019 Apr 2;129(5):1946-1959. doi: 10.1172/JCI124793. eCollection 2019 Apr 2. J Clin Invest. 2019. PMID: 30730305 Free PMC article.
22 results