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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 2
2003 1
2006 1
2007 1
2008 1
2009 2
2011 1
2012 5
2013 1
2015 5
2016 4
2017 4
2018 6
2019 6
2020 9
2021 11
2022 7
2023 4
2024 2

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72 results

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Page 1
Discovery and Clinical Proof-of-Concept of RLY-2608, a First-in-Class Mutant-Selective Allosteric PI3Kα Inhibitor That Decouples Antitumor Activity from Hyperinsulinemia.
Varkaris A, Pazolli E, Gunaydin H, Wang Q, Pierce L, Boezio AA, Bulku A, DiPietro L, Fridrich C, Frost A, Giordanetto F, Hamilton EP, Harris K, Holliday M, Hunter TL, Iskandar A, Ji Y, Larivée A, LaRochelle JR, Lescarbeau A, Llambi F, Lormil B, Mader MM, Mar BG, Martin I, McLean TH, Michelsen K, Pechersky Y, Puente-Poushnejad E, Raynor K, Rogala D, Samadani R, Schram AM, Shortsleeves K, Swaminathan S, Tajmir S, Tan G, Tang Y, Valverde R, Wehrenberg B, Wilbur J, Williams BR, Zeng H, Zhang H, Walters WP, Wolf BB, Shaw DE, Bergstrom DA, Watters J, Fraser JS, Fortin PD, Kipp DR. Varkaris A, et al. Among authors: frost a. Cancer Discov. 2024 Feb 8;14(2):240-257. doi: 10.1158/2159-8290.CD-23-0944. Cancer Discov. 2024. PMID: 37916956 Free PMC article.
Structural mechanism of mitochondrial membrane remodelling by human OPA1.
von der Malsburg A, Sapp GM, Zuccaro KE, von Appen A, Moss FR 3rd, Kalia R, Bennett JA, Abriata LA, Dal Peraro M, van der Laan M, Frost A, Aydin H. von der Malsburg A, et al. Among authors: frost a. Nature. 2023 Aug;620(7976):1101-1108. doi: 10.1038/s41586-023-06441-6. Epub 2023 Aug 23. Nature. 2023. PMID: 37612504 Free PMC article.
Influence of geography, stroke timing, and weather conditions on transport and workflow times: Results from a longitudinal 5-year Canadian provincial registry.
Kashani N, Ospel JM, Singh N, Zhou A, Ganesh A, Holodinsky JK, Almekhlafi M, Fouladirad S, Frost A, Yang L, Otani R, Newton B, Persad A, Wasyliw S, Graham BR, Hunter G, Gardner A, Cooley R, Ahmed SU, Peeling L, Kelly ME. Kashani N, et al. Among authors: frost a. Interv Neuroradiol. 2023 Aug 22:15910199231196614. doi: 10.1177/15910199231196614. Online ahead of print. Interv Neuroradiol. 2023. PMID: 37608547 Free article.
Structural basis of TRPV1 modulation by endogenous bioactive lipids.
Arnold WR, Mancino A, Moss FR, Frost A, Julius D, Cheng Y. Arnold WR, et al. Among authors: frost a. bioRxiv [Preprint]. 2023 Sep 19:2023.05.11.540281. doi: 10.1101/2023.05.11.540281. bioRxiv. 2023. PMID: 37292745 Free PMC article. Updated. Preprint.
A structural biology community assessment of AlphaFold2 applications.
Akdel M, Pires DEV, Pardo EP, Jänes J, Zalevsky AO, Mészáros B, Bryant P, Good LL, Laskowski RA, Pozzati G, Shenoy A, Zhu W, Kundrotas P, Serra VR, Rodrigues CHM, Dunham AS, Burke D, Borkakoti N, Velankar S, Frost A, Basquin J, Lindorff-Larsen K, Bateman A, Kajava AV, Valencia A, Ovchinnikov S, Durairaj J, Ascher DB, Thornton JM, Davey NE, Stein A, Elofsson A, Croll TI, Beltrao P. Akdel M, et al. Among authors: frost a. Nat Struct Mol Biol. 2022 Nov;29(11):1056-1067. doi: 10.1038/s41594-022-00849-w. Epub 2022 Nov 7. Nat Struct Mol Biol. 2022. PMID: 36344848 Free PMC article.
Structure and functionality of a multimeric human COQ7:COQ9 complex.
Manicki M, Aydin H, Abriata LA, Overmyer KA, Guerra RM, Coon JJ, Dal Peraro M, Frost A, Pagliarini DJ. Manicki M, et al. Among authors: frost a. Mol Cell. 2022 Nov 17;82(22):4307-4323.e10. doi: 10.1016/j.molcel.2022.10.003. Epub 2022 Oct 27. Mol Cell. 2022. PMID: 36306796 Free PMC article.
72 results