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Page 1
Post-transcriptional control of a stemness signature by RNA-binding protein MEX3A regulates murine adult neurogenesis.
Domingo-Muelas A, Duart-Abadia P, Morante-Redolat JM, Jordán-Pla A, Belenguer G, Fabra-Beser J, Paniagua-Herranz L, Pérez-Villalba A, Álvarez-Varela A, Barriga FM, Gil-Sanz C, Ortega F, Batlle E, Fariñas I. Domingo-Muelas A, et al. Among authors: alvarez varela a. Nat Commun. 2023 Jan 23;14(1):373. doi: 10.1038/s41467-023-36054-6. Nat Commun. 2023. PMID: 36690670 Free PMC article.
Metastatic recurrence in colorectal cancer arises from residual EMP1+ cells.
Cañellas-Socias A, Cortina C, Hernando-Momblona X, Palomo-Ponce S, Mulholland EJ, Turon G, Mateo L, Conti S, Roman O, Sevillano M, Slebe F, Stork D, Caballé-Mestres A, Berenguer-Llergo A, Álvarez-Varela A, Fenderico N, Novellasdemunt L, Jiménez-Gracia L, Sipka T, Bardia L, Lorden P, Colombelli J, Heyn H, Trepat X, Tejpar S, Sancho E, Tauriello DVF, Leedham S, Attolini CS, Batlle E. Cañellas-Socias A, et al. Among authors: alvarez varela a. Nature. 2022 Nov;611(7936):603-613. doi: 10.1038/s41586-022-05402-9. Epub 2022 Nov 9. Nature. 2022. PMID: 36352230 Free article.
Mex3a marks drug-tolerant persister colorectal cancer cells that mediate relapse after chemotherapy.
Álvarez-Varela A, Novellasdemunt L, Barriga FM, Hernando-Momblona X, Cañellas-Socias A, Cano-Crespo S, Sevillano M, Cortina C, Stork D, Morral C, Turon G, Slebe F, Jiménez-Gracia L, Caratù G, Jung P, Stassi G, Heyn H, Tauriello DVF, Mateo L, Tejpar S, Sancho E, Stephan-Otto Attolini C, Batlle E. Álvarez-Varela A, et al. Nat Cancer. 2022 Sep;3(9):1052-1070. doi: 10.1038/s43018-022-00402-0. Epub 2022 Jun 30. Nat Cancer. 2022. PMID: 35773527 Free article.
Mechanical compartmentalization of the intestinal organoid enables crypt folding and collective cell migration.
Pérez-González C, Ceada G, Greco F, Matejčić M, Gómez-González M, Castro N, Menendez A, Kale S, Krndija D, Clark AG, Gannavarapu VR, Álvarez-Varela A, Roca-Cusachs P, Batlle E, Vignjevic DM, Arroyo M, Trepat X. Pérez-González C, et al. Among authors: alvarez varela a. Nat Cell Biol. 2021 Jul;23(7):745-757. doi: 10.1038/s41556-021-00699-6. Epub 2021 Jun 21. Nat Cell Biol. 2021. PMID: 34155382 Free PMC article.
Benchmarking single-cell RNA-sequencing protocols for cell atlas projects.
Mereu E, Lafzi A, Moutinho C, Ziegenhain C, McCarthy DJ, Álvarez-Varela A, Batlle E, Sagar, Grün D, Lau JK, Boutet SC, Sanada C, Ooi A, Jones RC, Kaihara K, Brampton C, Talaga Y, Sasagawa Y, Tanaka K, Hayashi T, Braeuning C, Fischer C, Sauer S, Trefzer T, Conrad C, Adiconis X, Nguyen LT, Regev A, Levin JZ, Parekh S, Janjic A, Wange LE, Bagnoli JW, Enard W, Gut M, Sandberg R, Nikaido I, Gut I, Stegle O, Heyn H. Mereu E, et al. Among authors: alvarez varela a. Nat Biotechnol. 2020 Jun;38(6):747-755. doi: 10.1038/s41587-020-0469-4. Epub 2020 Apr 6. Nat Biotechnol. 2020. PMID: 32518403
Zonation of Ribosomal DNA Transcription Defines a Stem Cell Hierarchy in Colorectal Cancer.
Morral C, Stanisavljevic J, Hernando-Momblona X, Mereu E, Álvarez-Varela A, Cortina C, Stork D, Slebe F, Turon G, Whissell G, Sevillano M, Merlos-Suárez A, Casanova-Martí À, Moutinho C, Lowe SW, Dow LE, Villanueva A, Sancho E, Heyn H, Batlle E. Morral C, et al. Among authors: alvarez varela a. Cell Stem Cell. 2020 Jun 4;26(6):845-861.e12. doi: 10.1016/j.stem.2020.04.012. Epub 2020 May 11. Cell Stem Cell. 2020. PMID: 32396863 Free PMC article.
Apicobasal polarity controls lymphocyte adhesion to hepatic epithelial cells.
Reglero-Real N, Álvarez-Varela A, Cernuda-Morollón E, Feito J, Marcos-Ramiro B, Fernández-Martín L, Gómez-Lechón MJ, Muntané J, Sandoval P, Majano PL, Correas I, Alonso MA, Millán J. Reglero-Real N, et al. Among authors: alvarez varela a. Cell Rep. 2014 Sep 25;8(6):1879-1893. doi: 10.1016/j.celrep.2014.08.007. Epub 2014 Sep 18. Cell Rep. 2014. PMID: 25242329 Free article.