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Partial Inhibition of Glycolysis Reduces Atherogenesis Independent of Intraplaque Neovascularization in Mice.
Perrotta P, Van der Veken B, Van Der Veken P, Pintelon I, Roosens L, Adriaenssens E, Timmerman V, Guns PJ, De Meyer GRY, Martinet W. Perrotta P, et al. Among authors: adriaenssens e. Arterioscler Thromb Vasc Biol. 2020 May;40(5):1168-1181. doi: 10.1161/ATVBAHA.119.313692. Epub 2020 Mar 19. Arterioscler Thromb Vasc Biol. 2020. PMID: 32188275 Free PMC article.
Molecular Chaperones in the Pathogenesis of Amyotrophic Lateral Sclerosis: The Role of HSPB1.
Capponi S, Geuens T, Geroldi A, Origone P, Verdiani S, Cichero E, Adriaenssens E, De Winter V, Bandettini di Poggio M, Barberis M, Chiò A, Fossa P, Mandich P, Bellone E, Timmerman V. Capponi S, et al. Among authors: adriaenssens e. Hum Mutat. 2016 Nov;37(11):1202-1208. doi: 10.1002/humu.23062. Epub 2016 Aug 30. Hum Mutat. 2016. PMID: 27492805 Free PMC article.
Axonal Neuropathies due to Mutations in Small Heat Shock Proteins: Clinical, Genetic, and Functional Insights into Novel Mutations.
Echaniz-Laguna A, Geuens T, Petiot P, Péréon Y, Adriaenssens E, Haidar M, Capponi S, Maisonobe T, Fournier E, Dubourg O, Degos B, Salachas F, Lenglet T, Eymard B, Delmont E, Pouget J, Juntas Morales R, Goizet C, Latour P, Timmerman V, Stojkovic T. Echaniz-Laguna A, et al. Among authors: adriaenssens e. Hum Mutat. 2017 May;38(5):556-568. doi: 10.1002/humu.23189. Epub 2017 Feb 25. Hum Mutat. 2017. PMID: 28144995
Biallelic VARS variants cause developmental encephalopathy with microcephaly that is recapitulated in vars knockout zebrafish.
Siekierska A, Stamberger H, Deconinck T, Oprescu SN, Partoens M, Zhang Y, Sourbron J, Adriaenssens E, Mullen P, Wiencek P, Hardies K, Lee JS, Giong HK, Distelmaier F, Elpeleg O, Helbig KL, Hersh J, Isikay S, Jordan E, Karaca E, Kecskes A, Lupski JR, Kovacs-Nagy R, May P, Narayanan V, Pendziwiat M, Ramsey K, Rangasamy S, Shinde DN, Spiegel R, Timmerman V, von Spiczak S, Helbig I; C4RCD Research Group; AR working group of the EuroEPINOMICS RES Consortium; Weckhuysen S, Francklyn C, Antonellis A, de Witte P, De Jonghe P. Siekierska A, et al. Among authors: adriaenssens e. Nat Commun. 2019 Feb 12;10(1):708. doi: 10.1038/s41467-018-07953-w. Nat Commun. 2019. PMID: 30755616 Free PMC article.
Small heat shock proteins in neurodegenerative diseases.
Vendredy L, Adriaenssens E, Timmerman V. Vendredy L, et al. Among authors: adriaenssens e. Cell Stress Chaperones. 2020 Jul;25(4):679-699. doi: 10.1007/s12192-020-01101-4. Epub 2020 Apr 22. Cell Stress Chaperones. 2020. PMID: 32323160 Free PMC article. Review.
A weakened interface in the P182L variant of HSP27 associated with severe Charcot-Marie-Tooth neuropathy causes aberrant binding to interacting proteins.
Alderson TR, Adriaenssens E, Asselbergh B, Pritišanac I, Van Lent J, Gastall HY, Wälti MA, Louis JM, Timmerman V, Baldwin AJ, Lp Benesch J. Alderson TR, et al. Among authors: adriaenssens e. EMBO J. 2021 Apr 15;40(8):e103811. doi: 10.15252/embj.2019103811. Epub 2021 Mar 1. EMBO J. 2021. PMID: 33644875 Free PMC article.
171 results