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Targeting BRCA1-BER deficient breast cancer by ATM or DNA-PKcs blockade either alone or in combination with cisplatin for personalized therapy.
Albarakati N, Abdel-Fatah TM, Doherty R, Russell R, Agarwal D, Moseley P, Perry C, Arora A, Alsubhi N, Seedhouse C, Rakha EA, Green A, Ball G, Chan S, Caldas C, Ellis IO, Madhusudan S. Albarakati N, et al. Among authors: agarwal d. Mol Oncol. 2015 Jan;9(1):204-17. doi: 10.1016/j.molonc.2014.08.001. Epub 2014 Aug 27. Mol Oncol. 2015. PMID: 25205036 Free PMC article. Clinical Trial.
Single-strand selective monofunctional uracil-DNA glycosylase (SMUG1) deficiency is linked to aggressive breast cancer and predicts response to adjuvant therapy.
Abdel-Fatah TM, Albarakati N, Bowell L, Agarwal D, Moseley P, Hawkes C, Ball G, Chan S, Ellis IO, Madhusudan S. Abdel-Fatah TM, et al. Among authors: agarwal d. Breast Cancer Res Treat. 2013 Dec;142(3):515-27. doi: 10.1007/s10549-013-2769-6. Epub 2013 Nov 20. Breast Cancer Res Treat. 2013. PMID: 24253812
DNA polymerase β deficiency is linked to aggressive breast cancer: a comprehensive analysis of gene copy number, mRNA and protein expression in multiple cohorts.
Abdel-Fatah TM, Russell R, Agarwal D, Moseley P, Abayomi MA, Perry C, Albarakati N, Ball G, Chan S, Caldas C, Ellis IO, Madhusudan S. Abdel-Fatah TM, et al. Among authors: agarwal d. Mol Oncol. 2014 May;8(3):520-32. doi: 10.1016/j.molonc.2014.01.001. Epub 2014 Jan 10. Mol Oncol. 2014. PMID: 24462520 Free PMC article.
Genomic and protein expression analysis reveals flap endonuclease 1 (FEN1) as a key biomarker in breast and ovarian cancer.
Abdel-Fatah TM, Russell R, Albarakati N, Maloney DJ, Dorjsuren D, Rueda OM, Moseley P, Mohan V, Sun H, Abbotts R, Mukherjee A, Agarwal D, Illuzzi JL, Jadhav A, Simeonov A, Ball G, Chan S, Caldas C, Ellis IO, Wilson DM 3rd, Madhusudan S. Abdel-Fatah TM, et al. Among authors: agarwal d. Mol Oncol. 2014 Oct;8(7):1326-38. doi: 10.1016/j.molonc.2014.04.009. Epub 2014 May 13. Mol Oncol. 2014. PMID: 24880630 Free PMC article.
Adverse prognostic and predictive significance of low DNA-dependent protein kinase catalytic subunit (DNA-PKcs) expression in early-stage breast cancers.
Abdel-Fatah T, Arora A, Agarwal D, Moseley P, Perry C, Thompson N, Green AR, Rakha E, Chan S, Ball G, Ellis IO, Madhusudan S. Abdel-Fatah T, et al. Among authors: agarwal d. Breast Cancer Res Treat. 2014 Jul;146(2):309-20. doi: 10.1007/s10549-014-3035-2. Epub 2014 Jun 28. Breast Cancer Res Treat. 2014. PMID: 24972688
Untangling the ATR-CHEK1 network for prognostication, prediction and therapeutic target validation in breast cancer.
Abdel-Fatah TM, Middleton FK, Arora A, Agarwal D, Chen T, Moseley PM, Perry C, Doherty R, Chan S, Green AR, Rakha E, Ball G, Ellis IO, Curtin NJ, Madhusudan S. Abdel-Fatah TM, et al. Among authors: agarwal d. Mol Oncol. 2015 Mar;9(3):569-85. doi: 10.1016/j.molonc.2014.10.013. Epub 2014 Nov 6. Mol Oncol. 2015. PMID: 25468710 Free PMC article.
Transcriptomic and Protein Expression Analysis Reveals Clinicopathological Significance of Bloom Syndrome Helicase (BLM) in Breast Cancer.
Arora A, Abdel-Fatah TM, Agarwal D, Doherty R, Moseley PM, Aleskandarany MA, Green AR, Ball G, Alshareeda AT, Rakha EA, Chan SY, Ellis IO, Madhusudan S. Arora A, et al. Among authors: agarwal d. Mol Cancer Ther. 2015 Apr;14(4):1057-65. doi: 10.1158/1535-7163.MCT-14-0939. Epub 2015 Feb 11. Mol Cancer Ther. 2015. PMID: 25673821
SPAG5 as a prognostic biomarker and chemotherapy sensitivity predictor in breast cancer: a retrospective, integrated genomic, transcriptomic, and protein analysis.
Abdel-Fatah TMA, Agarwal D, Liu DX, Russell R, Rueda OM, Liu K, Xu B, Moseley PM, Green AR, Pockley AG, Rees RC, Caldas C, Ellis IO, Ball GR, Chan SYT. Abdel-Fatah TMA, et al. Among authors: agarwal d. Lancet Oncol. 2016 Jul;17(7):1004-1018. doi: 10.1016/S1470-2045(16)00174-1. Epub 2016 Jun 14. Lancet Oncol. 2016. PMID: 27312051 Clinical Trial.
1,250 results