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TNF-α synergises with IFN-γ to induce caspase-8-JAK1/2-STAT1-dependent death of intestinal epithelial cells.
Woznicki JA, Saini N, Flood P, Rajaram S, Lee CM, Stamou P, Skowyra A, Bustamante-Garrido M, Regazzoni K, Crawford N, McDade SS, Longley DB, Aza-Blanc P, Shanahan F, Zulquernain SA, McCarthy J, Melgar S, McRae BL, Nally K. Woznicki JA, et al. Among authors: skowyra a. Cell Death Dis. 2021 Sep 23;12(10):864. doi: 10.1038/s41419-021-04151-3. Cell Death Dis. 2021. PMID: 34556638 Free PMC article.
DNA sensor-associated type I interferon signaling is increased in ulcerative colitis and induces JAK-dependent inflammatory cell death in colonic organoids.
Flood P, Fanning A, Woznicki JA, Crowley T, Christopher A, Vaccaro A, Houston A, McSweeney S, Ross S, Hogan A, Brint E, Skowyra A, Bustamante M, Ambrose M, Moloney G, MacSharry J, Hammarström ML, Hurley M, Fitzgibbons C, Quigley EMM, Shanahan F, Zulquernain SA, McCarthy J, Dodson GS, Dabbagh K, McRae BL, Melgar S, Nally K. Flood P, et al. Among authors: skowyra a. Am J Physiol Gastrointest Liver Physiol. 2022 Nov 1;323(5):G439-G460. doi: 10.1152/ajpgi.00104.2022. Epub 2022 Sep 27. Am J Physiol Gastrointest Liver Physiol. 2022. PMID: 36165492 Free article.
Timed degradation of Mcl-1 controls mitotic cell death.
Clarke PR, Allan LA, Skowyra A. Clarke PR, et al. Among authors: skowyra a. Mol Cell Oncol. 2018 Oct 11;5(6):e1516450. doi: 10.1080/23723556.2018.1516450. eCollection 2018. Mol Cell Oncol. 2018. PMID: 30525093 Free PMC article.
12-month interim results of a prospective study of patients with mild to moderate open-angle glaucoma undergoing combined viscodilation of Schlemm's canal and collector channels and 360° trabeculotomy as a standalone procedure or combined with cataract surgery.
Grabska-Liberek I, Duda P, Rogowska M, Majszyk-Ionescu J, Skowyra A, Koziorowska A, Kane I, Chmielewski J. Grabska-Liberek I, et al. Among authors: skowyra a. Eur J Ophthalmol. 2022 Jan;32(1):309-315. doi: 10.1177/1120672121998234. Epub 2021 Feb 24. Eur J Ophthalmol. 2022. PMID: 33626924 Free PMC article.