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Caspase-mediated cleavage of Beclin-1 inactivates Beclin-1-induced autophagy and enhances apoptosis by promoting the release of proapoptotic factors from mitochondria.
Wirawan E, Vande Walle L, Kersse K, Cornelis S, Claerhout S, Vanoverberghe I, Roelandt R, De Rycke R, Verspurten J, Declercq W, Agostinis P, Vanden Berghe T, Lippens S, Vandenabeele P. Wirawan E, et al. Among authors: agostinis p. Cell Death Dis. 2010;1(1):e18. doi: 10.1038/cddis.2009.16. Cell Death Dis. 2010. PMID: 21364619 Free PMC article.
18th Euroconference on Apoptosis in Ghent, Belgium, 1-4 September 2010.
Declercq W, Agostinis P, Vandenabeele P. Declercq W, et al. Among authors: agostinis p. Cell Death Differ. 2011 Sep;18(9):1540-2. doi: 10.1038/cdd.2011.76. Epub 2011 Jun 3. Cell Death Differ. 2011. PMID: 21637287 Free PMC article. No abstract available.
The activation of the c-Jun N-terminal kinase and p38 mitogen-activated protein kinase signaling pathways protects HeLa cells from apoptosis following photodynamic therapy with hypericin.
Assefa Z, Vantieghem A, Declercq W, Vandenabeele P, Vandenheede JR, Merlevede W, de Witte P, Agostinis P. Assefa Z, et al. Among authors: agostinis p. J Biol Chem. 1999 Mar 26;274(13):8788-96. doi: 10.1074/jbc.274.13.8788. J Biol Chem. 1999. PMID: 10085120 Free article.
265 results