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A novel heterocyclic compound improves working memory in the radial arm maze and modulates the dopamine receptor D1R in frontal cortex of the Sprague-Dawley rat.
Hussein AM, Aher YD, Kalaba P, Aher NY, Dragačević V, Radoman B, Ilić M, Leban J, Beryozkina T, Ahmed ABMA, Urban E, Langer T, Lubec G. Hussein AM, et al. Among authors: aher ny. Behav Brain Res. 2017 Aug 14;332:308-315. doi: 10.1016/j.bbr.2017.06.023. Epub 2017 Jun 16. Behav Brain Res. 2017. PMID: 28629964
A novel heterocyclic compound targeting the dopamine transporter improves performance in the radial arm maze and modulates dopamine receptors D1-D3.
Saroja SR, Aher YD, Kalaba P, Aher NY, Zehl M, Korz V, Subramaniyan S, Miklosi AG, Zanon L, Neuhaus W, Höger H, Langer T, Urban E, Leban J, Lubec G. Saroja SR, et al. Among authors: aher ny. Behav Brain Res. 2016 Oct 1;312:127-37. doi: 10.1016/j.bbr.2016.06.011. Epub 2016 Jun 8. Behav Brain Res. 2016. PMID: 27288589
Heterocyclic Analogues of Modafinil as Novel, Atypical Dopamine Transporter Inhibitors.
Kalaba P, Aher NY, Ilić M, Dragačević V, Wieder M, Miklosi AG, Zehl M, Wackerlig J, Roller A, Beryozkina T, Radoman B, Saroja SR, Lindner W, Gonzalez EP, Bakulev V, Leban JJ, Sitte HH, Urban E, Langer T, Lubec G. Kalaba P, et al. Among authors: aher ny. J Med Chem. 2017 Nov 22;60(22):9330-9348. doi: 10.1021/acs.jmedchem.7b01313. Epub 2017 Nov 9. J Med Chem. 2017. PMID: 29091428
A daily single dose of a novel modafinil analogue CE-123 improves memory acquisition and memory retrieval.
Kristofova M, Aher YD, Ilic M, Radoman B, Kalaba P, Dragacevic V, Aher NY, Leban J, Korz V, Zanon L, Neuhaus W, Wieder M, Langer T, Urban E, Sitte HH, Hoeger H, Lubec G, Aradska J. Kristofova M, et al. Among authors: aher ny. Behav Brain Res. 2018 May 2;343:83-94. doi: 10.1016/j.bbr.2018.01.032. Epub 2018 Feb 1. Behav Brain Res. 2018. PMID: 29410048
Structure-Activity Relationships of Novel Thiazole-Based Modafinil Analogues Acting at Monoamine Transporters.
Kalaba P, Ilić M, Aher NY, Dragačević V, Wieder M, Zehl M, Wackerlig J, Beyl S, Sartori SB, Ebner K, Roller A, Lukic N, Beryozkina T, Gonzalez ERP, Neill P, Khan JA, Bakulev V, Leban JJ, Hering S, Pifl C, Singewald N, Lubec J, Urban E, Sitte HH, Langer T, Lubec G. Kalaba P, et al. Among authors: aher ny. J Med Chem. 2020 Jan 9;63(1):391-417. doi: 10.1021/acs.jmedchem.9b01938. Epub 2019 Dec 30. J Med Chem. 2020. PMID: 31841637
Low-Affinity/High-Selectivity Dopamine Transport Inhibition Sufficient to Rescue Cognitive Functions in the Aging Rat.
Lubec J, Hussein AM, Kalaba P, Feyissa DD, Arias-Sandoval E, Cybulska-Klosowicz A, Bezu M, Stojanovic T, Korz V, Malikovic J, Aher NY, Zehl M, Dragacevic V, Leban JJ, Sagheddu C, Wackerlig J, Pistis M, Correa M, Langer T, Urban E, Höger H, Lubec G. Lubec J, et al. Among authors: aher ny. Biomolecules. 2023 Mar 3;13(3):467. doi: 10.3390/biom13030467. Biomolecules. 2023. PMID: 36979402 Free PMC article.