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IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis.
Vince JE, Wong WW, Khan N, Feltham R, Chau D, Ahmed AU, Benetatos CA, Chunduru SK, Condon SM, McKinlay M, Brink R, Leverkus M, Tergaonkar V, Schneider P, Callus BA, Koentgen F, Vaux DL, Silke J. Vince JE, et al. Among authors: ahmed au. Cell. 2007 Nov 16;131(4):682-93. doi: 10.1016/j.cell.2007.10.037. Cell. 2007. PMID: 18022363 Free article.
In mouse embryonic fibroblasts, neither caspase-8 nor cellular FLICE-inhibitory protein (FLIP) is necessary for TNF to activate NF-κB, but caspase-8 is required for TNF to cause cell death, and induction of FLIP by NF-κB is required to prevent it.
Moujalled DM, Cook WD, Lluis JM, Khan NR, Ahmed AU, Callus BA, Vaux DL. Moujalled DM, et al. Among authors: ahmed au. Cell Death Differ. 2012 May;19(5):808-15. doi: 10.1038/cdd.2011.151. Epub 2011 Nov 18. Cell Death Differ. 2012. PMID: 22095280 Free PMC article.
CARP2 deficiency does not alter induction of NF-kappaB by TNFalpha.
Ahmed AU, Moulin M, Coumailleau F, Wong WW, Miasari M, Carter H, Silke J, Cohen-Tannoudji M, Vince JE, Vaux DL. Ahmed AU, et al. Curr Biol. 2009 Jan 13;19(1):R15-7; author reply R17-9. doi: 10.1016/j.cub.2008.11.040. Curr Biol. 2009. PMID: 19138581 Free article. No abstract available.
Genomic analysis of human brain metastases treated with stereotactic radiosurgery reveals unique signature based on treatment failure.
Shireman JM, White Q, Ni Z, Mohanty C, Cai Y, Zhao L, Agrawal N, Gonugunta N, Wang X, Mccarthy L, Kasulabada V, Pattnaik A, Ahmed AU, Miller J, Kulwin C, Cohen-Gadol A, Payner T, Lin CT, Savage JJ, Lane B, Shiue K, Kamer A, Shah M, Iyer G, Watson G, Kendziorski C, Dey M. Shireman JM, et al. Among authors: ahmed au. iScience. 2024 Mar 27;27(4):109601. doi: 10.1016/j.isci.2024.109601. eCollection 2024 Apr 19. iScience. 2024. PMID: 38623341 Free PMC article.
134 results