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Metformin Is a Pyridoxal-5'-phosphate (PLP)-Competitive Inhibitor of SHMT2.
Tramonti A, Cuyàs E, Encinar JA, Pietzke M, Paone A, Verdura S, Arbusà A, Martin-Castillo B, Giardina G, Joven J, Vazquez A, Contestabile R, Cutruzzolà F, Menendez JA. Tramonti A, et al. Among authors: arbusa a. Cancers (Basel). 2021 Aug 9;13(16):4009. doi: 10.3390/cancers13164009. Cancers (Basel). 2021. PMID: 34439169 Free PMC article.
Fatty acid synthase (FASN) regulates the mitochondrial priming of cancer cells.
Schroeder B, Vander Steen T, Espinoza I, Venkatapoorna CMK, Hu Z, Silva FM, Regan K, Cuyàs E, Meng XW, Verdura S, Arbusà A, Schneider PA, Flatten KS, Kemble G, Montero J, Kaufmann SH, Menendez JA, Lupu R. Schroeder B, et al. Among authors: arbusa a. Cell Death Dis. 2021 Oct 21;12(11):977. doi: 10.1038/s41419-021-04262-x. Cell Death Dis. 2021. PMID: 34675185 Free PMC article.
Clinical Management of COVID-19 in Cancer Patients with the STAT3 Inhibitor Silibinin.
Bosch-Barrera J, Roqué A, Teixidor E, Carmona-Garcia MC, Arbusà A, Brunet J, Martin-Castillo B, Cuyàs E, Verdura S, Menendez JA. Bosch-Barrera J, et al. Among authors: arbusa a. Pharmaceuticals (Basel). 2021 Dec 24;15(1):19. doi: 10.3390/ph15010019. Pharmaceuticals (Basel). 2021. PMID: 35056076 Free PMC article.