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2020 2
2021 5
2022 4
2024 1

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11 results

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Page 1
Ancestry-driven recalibration of tumor mutational burden and disparate clinical outcomes in response to immune checkpoint inhibitors.
Nassar AH, Adib E, Abou Alaiwi S, El Zarif T, Groha S, Akl EW, Nuzzo PV, Mouhieddine TH, Perea-Chamblee T, Taraszka K, El-Khoury H, Labban M, Fong C, Arora KS, Labaki C, Xu W, Sonpavde G, Haddad RI, Mouw KW, Giannakis M, Hodi FS, Zaitlen N, Schoenfeld AJ, Schultz N, Berger MF, MacConaill LE, Ananda G, Kwiatkowski DJ, Choueiri TK, Schrag D, Carrot-Zhang J, Gusev A. Nassar AH, et al. Among authors: akl ew. Cancer Cell. 2022 Oct 10;40(10):1161-1172.e5. doi: 10.1016/j.ccell.2022.08.022. Epub 2022 Sep 29. Cancer Cell. 2022. PMID: 36179682 Free PMC article.
TFEB drives mTORC1 hyperactivation and kidney disease in Tuberous Sclerosis Complex.
Alesi N, Khabibullin D, Rosenthal DM, Akl EW, Cory PM, Alchoueiry M, Salem S, Daou M, Gibbons WF, Chen JA, Zhang L, Filippakis H, Graciotti L, Miceli C, Monfregola J, Vilardo C, Morroni M, Di Malta C, Napolitano G, Ballabio A, Henske EP. Alesi N, et al. Among authors: akl ew. Nat Commun. 2024 Jan 9;15(1):406. doi: 10.1038/s41467-023-44229-4. Nat Commun. 2024. PMID: 38195686 Free PMC article.
CDKN2A Alterations and Response to Immunotherapy in Solid Tumors.
Adib E, Nassar AH, Akl EW, Abou Alaiwi S, Nuzzo PV, Mouhieddine TH, Sonpavde G, Haddad RI, Mouw KW, Giannakis M, Hodi FS, Shukla SA, Gusev A, Braun DA, Choueiri TK, Kwiatkowski DJ. Adib E, et al. Among authors: akl ew. Clin Cancer Res. 2021 Jul 15;27(14):4025-4035. doi: 10.1158/1078-0432.CCR-21-0575. Epub 2021 Jun 1. Clin Cancer Res. 2021. PMID: 34074656 Free PMC article.
Trans-ethnic variation in germline variants of patients with renal cell carcinoma.
Abou Alaiwi S, Nassar AH, Adib E, Groha SM, Akl EW, McGregor BA, Esplin ED, Yang S, Hatchell K, Fusaro V, Nielsen S, Kwiatkowski DJ, Sonpavde GP, Pomerantz M, Garber JE, Freedman ML, Rana HQ, Gusev A, Choueiri TK. Abou Alaiwi S, et al. Among authors: akl ew. Cell Rep. 2021 Mar 30;34(13):108926. doi: 10.1016/j.celrep.2021.108926. Cell Rep. 2021. PMID: 33789101 Free article.
Therapeutic Targeting of DGKA-Mediated Macropinocytosis Leads to Phospholipid Reprogramming in Tuberous Sclerosis Complex.
Kovalenko A, Sanin A, Kosmas K, Zhang L, Wang J, Akl EW, Giannikou K, Probst CK, Hougard TR, Rue RW, Krymskaya VP, Asara JM, Lam HC, Kwiatkowski DJ, Henske EP, Filippakis H. Kovalenko A, et al. Among authors: akl ew. Cancer Res. 2021 Apr 15;81(8):2086-2100. doi: 10.1158/0008-5472.CAN-20-2218. Epub 2021 Feb 16. Cancer Res. 2021. PMID: 33593821 Free PMC article.
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