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Page 1
[1,2,4]Triazolo[3,4-b]benzothiazole Scaffold as Versatile Nicotinamide Mimic Allowing Nanomolar Inhibition of Different PARP Enzymes.
Murthy S, Nizi MG, Maksimainen MM, Massari S, Alaviuhkola J, Lippok BE, Vagaggini C, Sowa ST, Galera-Prat A, Ashok Y, Venkannagari H, Prunskaite-Hyyryläinen R, Dreassi E, Lüscher B, Korn P, Tabarrini O, Lehtiö L. Murthy S, et al. Among authors: galera prat a. J Med Chem. 2023 Jan 26;66(2):1301-1320. doi: 10.1021/acs.jmedchem.2c01460. Epub 2023 Jan 4. J Med Chem. 2023. PMID: 36598465 Free PMC article.
Nanomechanics of tip-link cadherins.
Oroz J, Galera-Prat A, Hervás R, Valbuena A, Fernández-Bravo D, Carrión-Vázquez M. Oroz J, et al. Among authors: galera prat a. Sci Rep. 2019 Sep 16;9(1):13306. doi: 10.1038/s41598-019-49518-x. Sci Rep. 2019. PMID: 31527607 Free PMC article.
Activity-Based Screening Assay for Mono-ADP-Ribosylhydrolases.
Wazir S, Maksimainen MM, Alanen HI, Galera-Prat A, Lehtiö L. Wazir S, et al. Among authors: galera prat a. SLAS Discov. 2021 Jan;26(1):67-76. doi: 10.1177/2472555220928911. Epub 2020 Jun 12. SLAS Discov. 2021. PMID: 32527186 Free article.
A molecular toolbox for ADP-ribosyl binding proteins.
Sowa ST, Galera-Prat A, Wazir S, Alanen HI, Maksimainen MM, Lehtiö L. Sowa ST, et al. Among authors: galera prat a. Cell Rep Methods. 2021 Dec 20;1(8):100121. doi: 10.1016/j.crmeth.2021.100121. Epub 2021 Nov 11. Cell Rep Methods. 2021. PMID: 34786571 Free PMC article.
Nanoscale Engineering of Designer Cellulosomes.
Gunnoo M, Cazade PA, Galera-Prat A, Nash MA, Czjzek M, Cieplak M, Alvarez B, Aguilar M, Karpol A, Gaub H, Carrión-Vázquez M, Bayer EA, Thompson D. Gunnoo M, et al. Among authors: galera prat a. Adv Mater. 2016 Jul;28(27):5619-47. doi: 10.1002/adma.201503948. Epub 2016 Jan 7. Adv Mater. 2016. PMID: 26748482
Impact of scaffoldin mechanostability on cellulosomal activity.
Galera-Prat A , Vera AM , Moraïs S , Vazana Y , Bayer EA , Carrión-Vázquez M . Galera-Prat A , et al. Biomater Sci. 2020 Jul 7;8(13):3601-3610. doi: 10.1039/c9bm02052g. Epub 2020 Mar 31. Biomater Sci. 2020. PMID: 32232253
Analogs of TIQ-A as inhibitors of human mono-ADP-ribosylating PARPs.
Maksimainen MM, Murthy S, Sowa ST, Galera-Prat A, Rolina E, Heiskanen JP, Lehtiö L. Maksimainen MM, et al. Among authors: galera prat a. Bioorg Med Chem. 2021 Dec 15;52:116511. doi: 10.1016/j.bmc.2021.116511. Epub 2021 Nov 10. Bioorg Med Chem. 2021. PMID: 34801828 Free article.
Development of a 1,2,4-Triazole-Based Lead Tankyrase Inhibitor: Part II.
Leenders RGG, Brinch SA, Sowa ST, Amundsen-Isaksen E, Galera-Prat A, Murthy S, Aertssen S, Smits JN, Nieczypor P, Damen E, Wegert A, Nazaré M, Lehtiö L, Waaler J, Krauss S. Leenders RGG, et al. Among authors: galera prat a. J Med Chem. 2021 Dec 23;64(24):17936-17949. doi: 10.1021/acs.jmedchem.1c01264. Epub 2021 Dec 8. J Med Chem. 2021. PMID: 34878777 Free PMC article.
33 results