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Year | Number of Results |
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Page 1
Pan-KRAS inhibitor disables oncogenic signalling and tumour growth.
Nature. 2023 Jul;619(7968):160-166. doi: 10.1038/s41586-023-06123-3. Epub 2023 May 31.
Nature. 2023.
PMID: 37258666
Free PMC article.
Chemical remodeling of a cellular chaperone to target the active state of mutant KRAS.
Schulze CJ, Seamon KJ, Zhao Y, Yang YC, Cregg J, Kim D, Tomlinson A, Choy TJ, Wang Z, Sang B, Pourfarjam Y, Lucas J, Cuevas-Navarro A, Ayala-Santos C, Vides A, Li C, Marquez A, Zhong M, Vemulapalli V, Weller C, Gould A, Whalen DM, Salvador A, Milin A, Saldajeno-Concar M, Dinglasan N, Chen A, Evans J, Knox JE, Koltun ES, Singh M, Nichols R, Wildes D, Gill AL, Smith JAM, Lito P.
Schulze CJ, et al. Among authors: vides a.
Science. 2023 Aug 18;381(6659):794-799. doi: 10.1126/science.adg9652. Epub 2023 Aug 17.
Science. 2023.
PMID: 37590355
Free PMC article.
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The G protein signaling regulator RGS3 enhances the GTPase activity of KRAS.
Li C, Vides A, Kim D, Xue JY, Zhao Y, Lito P.
Li C, et al. Among authors: vides a.
Science. 2021 Oct 8;374(6564):197-201. doi: 10.1126/science.abf1730. Epub 2021 Oct 7.
Science. 2021.
PMID: 34618566
Free PMC article.
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Rapid non-uniform adaptation to conformation-specific KRAS(G12C) inhibition.
Xue JY, Zhao Y, Aronowitz J, Mai TT, Vides A, Qeriqi B, Kim D, Li C, de Stanchina E, Mazutis L, Risso D, Lito P.
Xue JY, et al. Among authors: vides a.
Nature. 2020 Jan;577(7790):421-425. doi: 10.1038/s41586-019-1884-x. Epub 2020 Jan 8.
Nature. 2020.
PMID: 31915379
Free PMC article.
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An approach to suppress the evolution of resistance in BRAFV600E-mutant cancer.
Xue Y, Martelotto L, Baslan T, Vides A, Solomon M, Mai TT, Chaudhary N, Riely GJ, Li BT, Scott K, Cechhi F, Stierner U, Chadalavada K, de Stanchina E, Schwartz S, Hembrough T, Nanjangud G, Berger MF, Nilsson J, Lowe SW, Reis-Filho JS, Rosen N, Lito P.
Xue Y, et al. Among authors: vides a.
Nat Med. 2017 Aug;23(8):929-937. doi: 10.1038/nm.4369. Epub 2017 Jul 17.
Nat Med. 2017.
PMID: 28714990
Free PMC article.
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