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Mevinolin: a highly potent competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase and a cholesterol-lowering agent.
Alberts AW, Chen J, Kuron G, Hunt V, Huff J, Hoffman C, Rothrock J, Lopez M, Joshua H, Harris E, Patchett A, Monaghan R, Currie S, Stapley E, Albers-Schonberg G, Hensens O, Hirshfield J, Hoogsteen K, Liesch J, Springer J. Alberts AW, et al. Proc Natl Acad Sci U S A. 1980 Jul;77(7):3957-61. doi: 10.1073/pnas.77.7.3957. Proc Natl Acad Sci U S A. 1980. PMID: 6933445 Free PMC article.
Potent inhibitory effect of antibiotic 1233A on cholesterol biosynthesis which specifically blocks 3-hydroxy-3-methylglutaryl coenzyme A synthase.
Omura S, Tomoda H, Kumagai H, Greenspan MD, Yodkovitz JB, Chen JS, Alberts AW, Martin I, Mochales S, Monaghan RL, et al. Omura S, et al. Among authors: alberts aw. J Antibiot (Tokyo). 1987 Sep;40(9):1356-7. doi: 10.7164/antibiotics.40.1356. J Antibiot (Tokyo). 1987. PMID: 2890615 Free article. No abstract available.
Plasma mevalonate as a measure of cholesterol synthesis in man.
Parker TS, McNamara DJ, Brown CD, Kolb R, Ahrens EH Jr, Alberts AW, Tobert J, Chen J, De Schepper PJ. Parker TS, et al. Among authors: alberts aw. J Clin Invest. 1984 Sep;74(3):795-804. doi: 10.1172/JCI111495. J Clin Invest. 1984. PMID: 6565710 Free PMC article.
84 results