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Oncogenic Gαq activates RhoJ through PDZ-RhoGEF.
Cervantes-Villagrana RD, Color-Aparicio VM, Castillo-Kauil A, García-Jiménez I, Beltrán-Navarro YM, Reyes-Cruz G, Vázquez-Prado J. Cervantes-Villagrana RD, et al. Among authors: castillo kauil a. Int J Mol Sci. 2023 Oct 29;24(21):15734. doi: 10.3390/ijms242115734. Int J Mol Sci. 2023. PMID: 37958718 Free PMC article.
s directly drives PDZ-RhoGEF signaling to Cdc42.
Castillo-Kauil A, García-Jiménez I, Cervantes-Villagrana RD, Adame-García SR, Beltrán-Navarro YM, Gutkind JS, Reyes-Cruz G, Vázquez-Prado J. Castillo-Kauil A, et al. J Biol Chem. 2020 Dec 11;295(50):16920-16928. doi: 10.1074/jbc.AC120.015204. Epub 2020 Oct 6. J Biol Chem. 2020. PMID: 33023908 Free PMC article.
Gβγ mediates activation of Rho guanine nucleotide exchange factor ARHGEF17 that promotes metastatic lung cancer progression.
García-Jiménez I, Cervantes-Villagrana RD, Del-Río-Robles JE, Castillo-Kauil A, Beltrán-Navarro YM, García-Román J, Reyes-Cruz G, Vázquez-Prado J. García-Jiménez I, et al. Among authors: castillo kauil a. J Biol Chem. 2022 Jan;298(1):101440. doi: 10.1016/j.jbc.2021.101440. Epub 2021 Nov 20. J Biol Chem. 2022. PMID: 34808208 Free PMC article.
Endothelial cell sprouting driven by RhoJ directly activated by a membrane-anchored Intersectin 1 (ITSN1) RhoGEF module.
Color-Aparicio VM, Cervantes-Villagrana RD, García-Jiménez I, Beltrán-Navarro YM, Castillo-Kauil A, Escobar-Islas E, Reyes-Cruz G, Vázquez-Prado J. Color-Aparicio VM, et al. Among authors: castillo kauil a. Biochem Biophys Res Commun. 2020 Mar 26;524(1):109-116. doi: 10.1016/j.bbrc.2020.01.068. Epub 2020 Jan 21. Biochem Biophys Res Commun. 2020. PMID: 31980169
Zonula occludens-2 regulates Rho proteins activity and the development of epithelial cytoarchitecture and barrier function.
Raya-Sandino A, Castillo-Kauil A, Domínguez-Calderón A, Alarcón L, Flores-Benitez D, Cuellar-Perez F, López-Bayghen B, Chávez-Munguía B, Vázquez-Prado J, González-Mariscal L. Raya-Sandino A, et al. Among authors: castillo kauil a. Biochim Biophys Acta Mol Cell Res. 2017 Oct;1864(10):1714-1733. doi: 10.1016/j.bbamcr.2017.05.016. Epub 2017 May 26. Biochim Biophys Acta Mol Cell Res. 2017. PMID: 28554775 Free article.
Protein Kinase A (PKA) Type I Interacts with P-Rex1, a Rac Guanine Nucleotide Exchange Factor: EFFECT ON PKA LOCALIZATION AND P-Rex1 SIGNALING.
Chávez-Vargas L, Adame-García SR, Cervantes-Villagrana RD, Castillo-Kauil A, Bruystens JG, Fukuhara S, Taylor SS, Mochizuki N, Reyes-Cruz G, Vázquez-Prado J. Chávez-Vargas L, et al. Among authors: castillo kauil a. J Biol Chem. 2016 Mar 18;291(12):6182-99. doi: 10.1074/jbc.M115.712216. Epub 2016 Jan 21. J Biol Chem. 2016. PMID: 26797121 Free PMC article.