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Isolation and culture of primary human hepatocytes.
LeCluyse EL, Alexandre E, Hamilton GA, Viollon-Abadie C, Coon DJ, Jolley S, Richert L. LeCluyse EL, et al. Among authors: alexandre e. Methods Mol Biol. 2005;290:207-29. doi: 10.1385/1-59259-838-2:207. Methods Mol Biol. 2005. PMID: 15361665
Follow-up to the pre-validation of a harmonised protocol for assessment of CYP induction responses in freshly isolated and cryopreserved human hepatocytes with respect to culture format, treatment, positive reference inducers and incubation conditions.
Abadie-Viollon C, Martin H, Blanchard N, Pekthong D, Bachellier P, Mantion G, Heyd B, Schuler F, Coassolo P, Alexandre E, Richert L. Abadie-Viollon C, et al. Among authors: alexandre e. Toxicol In Vitro. 2010 Feb;24(1):346-56. doi: 10.1016/j.tiv.2009.05.021. Epub 2009 Jun 2. Toxicol In Vitro. 2010. PMID: 19497360
Inter-laboratory evaluation of the response of primary human hepatocyte cultures to model CYP inducers - a European Centre for Validation of Alternative Methods (ECVAM) - funded pre-validation study.
Richert L, Abadie C, Bonet A, Heyd B, Mantion G, Alexandre E, Bachellier P, Kingston S, Pattenden C, Illouz S, Dennison A, Hoffmann S, Coecke S. Richert L, et al. Among authors: alexandre e. Toxicol In Vitro. 2010 Feb;24(1):335-45. doi: 10.1016/j.tiv.2009.05.022. Epub 2009 Jun 2. Toxicol In Vitro. 2010. PMID: 19497361
Biokinetics of chlorpromazine in primary rat and human hepatocytes and human HepaRG cells after repeated exposure.
Broeders JJ, Parmentier C, Truisi GL, Jossé R, Alexandre E, Savary CC, Hewitt PG, Mueller SO, Guillouzo A, Richert L, van Eijkeren JC, Hermens JL, Blaauboer BJ. Broeders JJ, et al. Among authors: alexandre e. Toxicol In Vitro. 2015 Dec 25;30(1 Pt A):52-61. doi: 10.1016/j.tiv.2014.08.012. Epub 2014 Nov 4. Toxicol In Vitro. 2015. PMID: 25458484
127 results