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Neutrophil elastase selectively kills cancer cells and attenuates tumorigenesis.
Cui C, Chakraborty K, Tang XA, Zhou G, Schoenfelt KQ, Becker KM, Hoffman A, Chang YF, Blank A, Reardon CA, Kenny HA, Vaisar T, Lengyel E, Greene G, Becker L. Cui C, et al. Among authors: hoffman a. Cell. 2021 Jun 10;184(12):3163-3177.e21. doi: 10.1016/j.cell.2021.04.016. Epub 2021 May 7. Cell. 2021. PMID: 33964209 Free PMC article.
A lysosome-targeted DNA nanodevice selectively targets macrophages to attenuate tumours.
Cui C, Chakraborty K, Tang XA, Schoenfelt KQ, Hoffman A, Blank A, McBeth B, Pulliam N, Reardon CA, Kulkarni SA, Vaisar T, Ballabio A, Krishnan Y, Becker L. Cui C, et al. Among authors: hoffman a. Nat Nanotechnol. 2021 Dec;16(12):1394-1402. doi: 10.1038/s41565-021-00988-z. Epub 2021 Nov 11. Nat Nanotechnol. 2021. PMID: 34764452
Laminin-α4 Is Upregulated in Both Human and Murine Models of Obesity.
Goddi A, Carmona A, Schroedl L, White JM, Piron MJ, De Leon A, Casimiro I, Hoffman A, Gonzalez Porras MA, Brey EM, Brady MJ, Cohen RN. Goddi A, et al. Among authors: hoffman a. Front Endocrinol (Lausanne). 2021 Jul 28;12:698621. doi: 10.3389/fendo.2021.698621. eCollection 2021. Front Endocrinol (Lausanne). 2021. PMID: 34394003 Free PMC article.
Metabolically Activated Adipose Tissue Macrophages Perform Detrimental and Beneficial Functions during Diet-Induced Obesity.
Coats BR, Schoenfelt KQ, Barbosa-Lorenzi VC, Peris E, Cui C, Hoffman A, Zhou G, Fernandez S, Zhai L, Hall BA, Haka AS, Shah AM, Reardon CA, Brady MJ, Rhodes CJ, Maxfield FR, Becker L. Coats BR, et al. Among authors: hoffman a. Cell Rep. 2017 Sep 26;20(13):3149-3161. doi: 10.1016/j.celrep.2017.08.096. Cell Rep. 2017. PMID: 28954231 Free PMC article.