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Novel Insights into the Molecular Mechanisms Involved in the Neuroprotective Effects of C-Phycocyanin against Brain Ischemia in Rats.
Marín-Prida J, Liberato JL, Llópiz-Arzuaga A, Stringhetta-Padovani K, Pavón-Fuentes N, Leopoldino AM, Cruz OG, González IH, Pérez ML, Camins A, Ferreira Dos Santos W, Uyemura SA, Pardo-Andreu GL, Pentón-Rol G. Marín-Prida J, et al. Among authors: llopiz arzuaga a. Curr Pharm Des. 2022;28(14):1187-1197. doi: 10.2174/1381612828666220506145542. Curr Pharm Des. 2022. PMID: 35524676
Phycocyanobilin reduces brain injury after endothelin-1- induced focal cerebral ischaemia.
Pavón-Fuentes N, Marín-Prida J, Llópiz-Arzuaga A, Falcón-Cama V, Campos-Mojena R, Cervantes-Llanos M, Piniella-Matamoros B, Pentón-Arias E, Pentón-Rol G. Pavón-Fuentes N, et al. Among authors: llopiz arzuaga a. Clin Exp Pharmacol Physiol. 2020 Mar;47(3):383-392. doi: 10.1111/1440-1681.13214. Epub 2019 Dec 6. Clin Exp Pharmacol Physiol. 2020. PMID: 31732975
The effects of Phycocyanobilin on experimental arthritis involve the reduction in nociception and synovial neutrophil infiltration, inhibition of cytokine production, and modulation of the neuronal proteome.
Marín-Prida J, Rodríguez-Ulloa A, Besada V, Llopiz-Arzuaga A, Batista NV, Hernández-González I, Pavón-Fuentes N, Marciano Vieira ÉL, Falcón-Cama V, Acosta EF, Martínez-Donato G, Cervantes-Llanos M, Lingfeng D, González LJ, Fernández-Massó JR, Guillén-Nieto G, Pentón-Arias E, Amaral FA, Teixeira MM, Pentón-Rol G. Marín-Prida J, et al. Among authors: llopiz arzuaga a. Front Immunol. 2023 Oct 23;14:1227268. doi: 10.3389/fimmu.2023.1227268. eCollection 2023. Front Immunol. 2023. PMID: 37936684 Free PMC article.
Comparative Neuroregenerative Effects of C-Phycocyanin and IFN-Beta in a Model of Multiple Sclerosis in Mice.
Pentón-Rol G, Lagumersindez-Denis N, Muzio L, Bergami A, Furlan R, Fernández-Massó JR, Nazabal-Galvez M, Llópiz-Arzuaga A, Herrera-Rolo T, Veliz-Rodriguez T, Polentarutti N, Marín-Prida J, Raíces-Cruz I, Valenzuela-Silva C, Teixeira MM, Pentón-Arias E. Pentón-Rol G, et al. Among authors: llopiz arzuaga a. J Neuroimmune Pharmacol. 2016 Mar;11(1):153-67. doi: 10.1007/s11481-015-9642-9. Epub 2015 Nov 10. J Neuroimmune Pharmacol. 2016. PMID: 26556034
C-Phycocyanin is neuroprotective against global cerebral ischemia/reperfusion injury in gerbils.
Pentón-Rol G, Marín-Prida J, Pardo-Andreu G, Martínez-Sánchez G, Acosta-Medina EF, Valdivia-Acosta A, Lagumersindez-Denis N, Rodríguez-Jiménez E, Llópiz-Arzuaga A, López-Saura PA, Guillén-Nieto G, Pentón-Arias E. Pentón-Rol G, et al. Among authors: llopiz arzuaga a. Brain Res Bull. 2011 Aug 10;86(1-2):42-52. doi: 10.1016/j.brainresbull.2011.05.016. Epub 2011 Jun 6. Brain Res Bull. 2011. PMID: 21669260
C-Phycocyanin ameliorates experimental autoimmune encephalomyelitis and induces regulatory T cells.
Pentón-Rol G, Martínez-Sánchez G, Cervantes-Llanos M, Lagumersindez-Denis N, Acosta-Medina EF, Falcón-Cama V, Alonso-Ramírez R, Valenzuela-Silva C, Rodríguez-Jiménez E, Llópiz-Arzuaga A, Marín-Prida J, López-Saura PA, Guillén-Nieto GE, Pentón-Arias E. Pentón-Rol G, et al. Among authors: llopiz arzuaga a. Int Immunopharmacol. 2011 Jan;11(1):29-38. doi: 10.1016/j.intimp.2010.10.001. Epub 2010 Oct 23. Int Immunopharmacol. 2011. PMID: 20971186
Obtention and characterization of the recombinant simian Interleukin-15 in Escherichia coli for the preclinical assessment of an IL-15-based therapeutic vaccine.
Rodríguez-Álvarez Y, Martínez-Cordovez K, Llopiz-Arzuaga A, Ramos-Gómez Y, Besada-Pérez V, García-Lines D, Santos-Savio A. Rodríguez-Álvarez Y, et al. Among authors: llopiz arzuaga a. Prep Biochem Biotechnol. 2017 Oct 21;47(9):889-900. doi: 10.1080/10826068.2017.1365238. Epub 2017 Aug 17. Prep Biochem Biotechnol. 2017. PMID: 28816622
C-Phycocyanin protects SH-SY5Y cells from oxidative injury, rat retina from transient ischemia and rat brain mitochondria from Ca2+/phosphate-induced impairment.
Marín-Prida J, Pentón-Rol G, Rodrigues FP, Alberici LC, Stringhetta K, Leopoldino AM, Naal Z, Polizello AC, Llópiz-Arzuaga A, Rosa MN, Liberato JL, Santos WF, Uyemura SA, Pentón-Arias E, Curti C, Pardo-Andreu GL. Marín-Prida J, et al. Among authors: llopiz arzuaga a. Brain Res Bull. 2012 Dec 1;89(5-6):159-67. doi: 10.1016/j.brainresbull.2012.08.011. Epub 2012 Sep 7. Brain Res Bull. 2012. PMID: 22982368 Free article.
Phycocyanobilin promotes PC12 cell survival and modulates immune and inflammatory genes and oxidative stress markers in acute cerebral hypoperfusion in rats.
Marín-Prida J, Pavón-Fuentes N, Llópiz-Arzuaga A, Fernández-Massó JR, Delgado-Roche L, Mendoza-Marí Y, Santana SP, Cruz-Ramírez A, Valenzuela-Silva C, Nazábal-Gálvez M, Cintado-Benítez A, Pardo-Andreu GL, Polentarutti N, Riva F, Pentón-Arias E, Pentón-Rol G. Marín-Prida J, et al. Among authors: llopiz arzuaga a. Toxicol Appl Pharmacol. 2013 Oct 1;272(1):49-60. doi: 10.1016/j.taap.2013.05.021. Epub 2013 Jun 2. Toxicol Appl Pharmacol. 2013. PMID: 23732081