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Metformin inhibits 7,12-dimethylbenz[a]anthracene-induced breast carcinogenesis and adduct formation in human breast cells by inhibiting the cytochrome P4501A1/aryl hydrocarbon receptor signaling pathway.
Maayah ZH, Ghebeh H, Alhaider AA, El-Kadi AO, Soshilov AA, Denison MS, Ansari MA, Korashy HM. Maayah ZH, et al. Among authors: alhaider aa. Toxicol Appl Pharmacol. 2015 Apr 15;284(2):217-26. doi: 10.1016/j.taap.2015.02.007. Epub 2015 Feb 17. Toxicol Appl Pharmacol. 2015. PMID: 25697376
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