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Immunotherapy with interferon-alpha in patients affected by chronic hepatitis C induces an intercorrelated stimulation of the cytokine network and an increase in depressive and anxiety symptoms.
Bonaccorso S, Puzella A, Marino V, Pasquini M, Biondi M, Artini M, Almerighi C, Levrero M, Egyed B, Bosmans E, Meltzer HY, Maes M. Bonaccorso S, et al. Among authors: almerighi c. Psychiatry Res. 2001 Dec 15;105(1-2):45-55. doi: 10.1016/s0165-1781(01)00315-8. Psychiatry Res. 2001. PMID: 11740974 Clinical Trial.
Increased depressive ratings in patients with hepatitis C receiving interferon-alpha-based immunotherapy are related to interferon-alpha-induced changes in the serotonergic system.
Bonaccorso S, Marino V, Puzella A, Pasquini M, Biondi M, Artini M, Almerighi C, Verkerk R, Meltzer H, Maes M. Bonaccorso S, et al. Among authors: almerighi c. J Clin Psychopharmacol. 2002 Feb;22(1):86-90. doi: 10.1097/00004714-200202000-00014. J Clin Psychopharmacol. 2002. PMID: 11799348 Clinical Trial.
Treatment with interferon-alpha (IFN alpha) of hepatitis C patients induces lower serum dipeptidyl peptidase IV activity, which is related to IFN alpha-induced depressive and anxiety symptoms and immune activation.
Maes M, Bonaccorso S, Marino V, Puzella A, Pasquini M, Biondi M, Artini M, Almerighi C, Meltzer H. Maes M, et al. Among authors: almerighi c. Mol Psychiatry. 2001 Jul;6(4):475-80. doi: 10.1038/sj.mp.4000872. Mol Psychiatry. 2001. PMID: 11443537 Clinical Trial.
A simple rule to personalize standard dual therapy across all genotypes in naive chronic hepatitis C patients: the TT4 randomized trial.
Francioso S, Almerighi C, Forte P, Bandiera F, Nosotti L, Lionetti R, Taliani G, Piras MR, Ponti ML, Parruti G, Di Candilo F, Gentile S, Piccolo P, Salso A, Riccobelli F, Renzi S, Longo MA, Montalbano M, Zaru S, Biliotti E, Di Masi F, Santopaolo F, Angelico M. Francioso S, et al. Among authors: almerighi c. Dig Liver Dis. 2014 Feb;46(2):164-9. doi: 10.1016/j.dld.2013.10.002. Epub 2013 Nov 13. Dig Liver Dis. 2014. PMID: 24239044 Clinical Trial.
18 results