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Mutation of the proline P81 into a serine modifies the tumour suppressor function of the von Hippel-Lindau gene in the ccRCC.
Br J Cancer. 2022 Nov;127(11):1954-1962. doi: 10.1038/s41416-022-01985-2. Epub 2022 Sep 29.
Br J Cancer. 2022.
PMID: 36175619
Free PMC article.
The prefoldin complex stabilizes the von Hippel-Lindau protein against aggregation and degradation.
Chesnel F, Couturier A, Alusse A, Gagné JP, Poirier GG, Jean D, Boisvert FM, Hascoet P, Paillard L, Arlot-Bonnemains Y, Le Goff X.
Chesnel F, et al. Among authors: alusse a.
PLoS Genet. 2020 Nov 2;16(11):e1009183. doi: 10.1371/journal.pgen.1009183. eCollection 2020 Nov.
PLoS Genet. 2020.
PMID: 33137104
Free PMC article.
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