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Dendritic cell-targeted therapy expands CD8 T cell responses to bona-fide neoantigens in lung tumors.
López L, Morosi LG, La Terza F, Bourdely P, Rospo G, Amadio R, Piperno GM, Russo V, Volponi C, Vodret S, Joshi S, Giannese F, Lazarevic D, Germano G, Stoitzner P, Bardelli A, Dalod M, Pace L, Caronni N, Guermonprez P, Benvenuti F. López L, et al. Among authors: amadio r. Nat Commun. 2024 Mar 13;15(1):2280. doi: 10.1038/s41467-024-46685-y. Nat Commun. 2024. PMID: 38480738 Free PMC article.
Wiskott-Aldrich syndrome protein restricts cGAS/STING activation by dsDNA immune complexes.
Piperno GM, Naseem A, Silvestrelli G, Amadio R, Caronni N, Cervantes-Luevano KE, Liv N, Klumperman J, Colliva A, Ali H, Graziano F, Benaroch P, Haecker H, Hanna RN, Benvenuti F. Piperno GM, et al. Among authors: amadio r. JCI Insight. 2020 Sep 3;5(17):e132857. doi: 10.1172/jci.insight.132857. JCI Insight. 2020. PMID: 32721945 Free PMC article.
CXCL5-mediated accumulation of mature neutrophils in lung cancer tissues impairs the differentiation program of anticancer CD8 T cells and limits the efficacy of checkpoint inhibitors.
Simoncello F, Piperno GM, Caronni N, Amadio R, Cappelletto A, Canarutto G, Piazza S, Bicciato S, Benvenuti F. Simoncello F, et al. Among authors: amadio r. Oncoimmunology. 2022 Apr 7;11(1):2059876. doi: 10.1080/2162402X.2022.2059876. eCollection 2022. Oncoimmunology. 2022. PMID: 35402081 Free PMC article.