Ambaye N[Author] - Search Results

Year	Number of Results
2010	1
2011	3
2012	2
2013	2
2014	1
2015	2
2016	3
2018	1
2019	1
2020	1
2021	2
2024	0

1

Novel anti-cancer candidates from a combinatorial peptide library.

Ambaye ND, Yu HE. Ambaye ND, et al. Chem Biol Drug Des. 2021 Jan;97(1):87-96. doi: 10.1111/cbdd.13763. Epub 2020 Aug 26. Chem Biol Drug Des. 2021. PMID: 32659860

2

Potent antitumor effects of cell-penetrating peptides targeting STAT3 axis.

Aftabizadeh M, Li YJ, Zhao Q, Zhang C, Ambaye N, Song J, Nagao T, Lahtz C, Fakih M, Ann DK, Yu H, Herrmann A. Aftabizadeh M, et al. Among authors: ambaye n. JCI Insight. 2021 Jan 25;6(2):e136176. doi: 10.1172/jci.insight.136176. JCI Insight. 2021. PMID: 33491667 Free PMC article.

3

Noncovalent structure of SENP1 in complex with SUMO2.

Ambaye ND. Ambaye ND. Acta Crystallogr F Struct Biol Commun. 2019 May 1;75(Pt 5):332-339. doi: 10.1107/S2053230X19004266. Epub 2019 Apr 24. Acta Crystallogr F Struct Biol Commun. 2019. PMID: 31045562 Free PMC article.

4

RWD Domain as an E2 (Ubc9)-Interaction Module.

Alontaga AY, Ambaye ND, Li YJ, Vega R, Chen CH, Bzymek KP, Williams JC, Hu W, Chen Y. Alontaga AY, et al. Among authors: ambaye nd. J Biol Chem. 2015 Jul 3;290(27):16550-9. doi: 10.1074/jbc.M115.644047. Epub 2015 Apr 27. J Biol Chem. 2015. PMID: 25918163 Free PMC article.

5

Observation of an E2 (Ubc9)-homodimer by crystallography.

Alontaga AY, Ambaye ND, Li YJ, Vega R, Chen CH, Bzymek KP, Williams JC, Hu W, Chen Y. Alontaga AY, et al. Among authors: ambaye nd. Data Brief. 2016 Feb 12;7:195-200. doi: 10.1016/j.dib.2016.02.015. eCollection 2016 Jun. Data Brief. 2016. PMID: 27408909 Free PMC article.

6

Streptonigrin Inhibits SENP1 and Reduces the Protein Level of Hypoxia-Inducible Factor 1α (HIF1α) in Cells.

Ambaye N, Chen CH, Khanna S, Li YJ, Chen Y. Ambaye N, et al. Biochemistry. 2018 Mar 20;57(11):1807-1813. doi: 10.1021/acs.biochem.7b00947. Epub 2018 Mar 1. Biochemistry. 2018. PMID: 29481054 Free PMC article.

7

The discovery of phenylbenzamide derivatives as Grb7-based antitumor agents.

Ambaye ND, Gunzburg MJ, Lim RC, Price JT, Wilce MC, Wilce JA. Ambaye ND, et al. ChemMedChem. 2013 Feb;8(2):280-8. doi: 10.1002/cmdc.201200400. Epub 2012 Dec 17. ChemMedChem. 2013. PMID: 23355456

8

Identification of the first small-molecule inhibitor of the REV7 DNA repair protein interaction.

Actis ML, Ambaye ND, Evison BJ, Shao Y, Vanarotti M, Inoue A, McDonald ET, Kikuchi S, Heath R, Hara K, Hashimoto H, Fujii N. Actis ML, et al. Among authors: ambaye nd. Bioorg Med Chem. 2016 Sep 15;24(18):4339-4346. doi: 10.1016/j.bmc.2016.07.026. Epub 2016 Jul 16. Bioorg Med Chem. 2016. PMID: 27448776 Free PMC article.

9

Unexpected involvement of staple leads to redesign of selective bicyclic peptide inhibitor of Grb7.

Gunzburg MJ, Kulkarni K, Watson GM, Ambaye ND, Del Borgo MP, Brandt R, Pero SC, Perlmutter P, Wilce MC, Wilce JA. Gunzburg MJ, et al. Among authors: ambaye nd. Sci Rep. 2016 Jun 3;6:27060. doi: 10.1038/srep27060. Sci Rep. 2016. PMID: 27257138 Free PMC article.

10

Cyclic Peptides Incorporating Phosphotyrosine Mimetics as Potent and Specific Inhibitors of the Grb7 Breast Cancer Target.

Watson GM, Gunzburg MJ, Ambaye ND, Lucas WA, Traore DA, Kulkarni K, Cergol KM, Payne RJ, Panjikar S, Pero SC, Perlmutter P, Wilce MC, Wilce JA. Watson GM, et al. Among authors: ambaye nd. J Med Chem. 2015 Oct 8;58(19):7707-18. doi: 10.1021/acs.jmedchem.5b00609. Epub 2015 Sep 23. J Med Chem. 2015. PMID: 26359549

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