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Loss of the lupus autoantigen Ro52/Trim21 induces tissue inflammation and systemic autoimmunity by disregulating the IL-23-Th17 pathway.
Espinosa A, Dardalhon V, Brauner S, Ambrosi A, Higgs R, Quintana FJ, Sjöstrand M, Eloranta ML, Ní Gabhann J, Winqvist O, Sundelin B, Jefferies CA, Rozell B, Kuchroo VK, Wahren-Herlenius M. Espinosa A, et al. Among authors: ambrosi a. J Exp Med. 2009 Aug 3;206(8):1661-71. doi: 10.1084/jem.20090585. Epub 2009 Jul 27. J Exp Med. 2009. PMID: 19635858 Free PMC article.
Maternal MHC regulates generation of pathogenic antibodies and fetal MHC-encoded genes determine susceptibility in congenital heart block.
Strandberg LS, Ambrosi A, Jagodic M, Dzikaite V, Janson P, Khademi M, Salomonsson S, Ottosson L, Klauninger R, Adén U, Sonesson SE, Sunnerhagen M, de Graaf KL, Kuchroo VK, Achour A, Winqvist O, Olsson T, Wahren-Herlenius M. Strandberg LS, et al. Among authors: ambrosi a. J Immunol. 2010 Sep 15;185(6):3574-82. doi: 10.4049/jimmunol.1001396. Epub 2010 Aug 9. J Immunol. 2010. PMID: 20696861
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