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Year Number of Results
2015 3
2016 3
2018 1
2020 2
2021 1
2022 1
2023 1
2024 0

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Page 1
PI3K-C2β limits mTORC1 signaling and angiogenic growth.
Kobialka P, Llena J, Deleyto-Seldas N, Munar-Gelabert M, Dengra JA, Villacampa P, Albinyà-Pedrós A, Muixi L, Andrade J, van Splunder H, Angulo-Urarte A, Potente M, Grego-Bessa J, Castillo SD, Vanhaesebroeck B, Efeyan A, Graupera M. Kobialka P, et al. Among authors: angulo urarte a. Sci Signal. 2023 Nov 28;16(813):eadg1913. doi: 10.1126/scisignal.adg1913. Epub 2023 Nov 28. Sci Signal. 2023. PMID: 38015911
Phosphoinositide 3-Kinase-Regulated Pericyte Maturation Governs Vascular Remodeling.
Figueiredo AM, Villacampa P, Diéguez-Hurtado R, José Lozano J, Kobialka P, Cortazar AR, Martinez-Romero A, Angulo-Urarte A, Franco CA, Claret M, Aransay AM, Adams RH, Carracedo A, Graupera M. Figueiredo AM, et al. Among authors: angulo urarte a. Circulation. 2020 Aug 18;142(7):688-704. doi: 10.1161/CIRCULATIONAHA.119.042354. Epub 2020 May 29. Circulation. 2020. PMID: 32466671
Cell-cell junctions as sensors and transducers of mechanical forces.
Angulo-Urarte A, van der Wal T, Huveneers S. Angulo-Urarte A, et al. Biochim Biophys Acta Biomembr. 2020 Sep 1;1862(9):183316. doi: 10.1016/j.bbamem.2020.183316. Epub 2020 Apr 28. Biochim Biophys Acta Biomembr. 2020. PMID: 32360073 Free article. Review.
The onset of PI3K-related vascular malformations occurs during angiogenesis and is prevented by the AKT inhibitor miransertib.
Kobialka P, Sabata H, Vilalta O, Gouveia L, Angulo-Urarte A, Muixí L, Zanoncello J, Muñoz-Aznar O, Olaciregui NG, Fanlo L, Esteve-Codina A, Lavarino C, Javierre BM, Celis V, Rovira C, López-Fernández S, Baselga E, Mora J, Castillo SD, Graupera M. Kobialka P, et al. Among authors: angulo urarte a. EMBO Mol Med. 2022 Jul 7;14(7):e15619. doi: 10.15252/emmm.202115619. Epub 2022 Jun 13. EMBO Mol Med. 2022. PMID: 35695059 Free PMC article.
PI3K at the crossroads of tumor angiogenesis signaling pathways.
Soler A, Angulo-Urarte A, Graupera M. Soler A, et al. Among authors: angulo urarte a. Mol Cell Oncol. 2015 Feb 26;2(2):e975624. doi: 10.4161/23723556.2014.975624. eCollection 2015 Apr-Jun. Mol Cell Oncol. 2015. PMID: 27308431 Free PMC article. Review.
PTEN mediates Notch-dependent stalk cell arrest in angiogenesis.
Serra H, Chivite I, Angulo-Urarte A, Soler A, Sutherland JD, Arruabarrena-Aristorena A, Ragab A, Lim R, Malumbres M, Fruttiger M, Potente M, Serrano M, Fabra À, Viñals F, Casanovas O, Pandolfi PP, Bigas A, Carracedo A, Gerhardt H, Graupera M. Serra H, et al. Among authors: angulo urarte a. Nat Commun. 2015 Jul 31;6:7935. doi: 10.1038/ncomms8935. Nat Commun. 2015. PMID: 26228240 Free PMC article.
Endothelial cell rearrangements during vascular patterning require PI3-kinase-mediated inhibition of actomyosin contractility.
Angulo-Urarte A, Casado P, Castillo SD, Kobialka P, Kotini MP, Figueiredo AM, Castel P, Rajeeve V, Milà-Guasch M, Millan J, Wiesner C, Serra H, Muixi L, Casanovas O, Viñals F, Affolter M, Gerhardt H, Huveneers S, Belting HG, Cutillas PR, Graupera M. Angulo-Urarte A, et al. Nat Commun. 2018 Nov 16;9(1):4826. doi: 10.1038/s41467-018-07172-3. Nat Commun. 2018. PMID: 30446640 Free PMC article.
Somatic activating mutations in Pik3ca cause sporadic venous malformations in mice and humans.
Castillo SD, Tzouanacou E, Zaw-Thin M, Berenjeno IM, Parker VE, Chivite I, Milà-Guasch M, Pearce W, Solomon I, Angulo-Urarte A, Figueiredo AM, Dewhurst RE, Knox RG, Clark GR, Scudamore CL, Badar A, Kalber TL, Foster J, Stuckey DJ, David AL, Phillips WA, Lythgoe MF, Wilson V, Semple RK, Sebire NJ, Kinsler VA, Graupera M, Vanhaesebroeck B. Castillo SD, et al. Among authors: angulo urarte a. Sci Transl Med. 2016 Mar 30;8(332):332ra43. doi: 10.1126/scitranslmed.aad9982. Sci Transl Med. 2016. PMID: 27030595 Free PMC article.
11 results