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Large-scale expansions of Friedreich's ataxia GAA•TTC repeats in an experimental human system: role of DNA replication and prevention by LNA-DNA oligonucleotides and PNA oligomers.
Nucleic Acids Res. 2023 Sep 8;51(16):8532-8549. doi: 10.1093/nar/gkad441.
Nucleic Acids Res. 2023.
PMID: 37216608
Free PMC article.
Pathogenic CANVAS (AAGGG)n repeats stall DNA replication due to the formation of alternative DNA structures.
Hisey JA, Radchenko EA, Mandel NH, McGinty RJ, Matos-Rodrigues G, Rastokina A, Masnovo C, Ceschi S, Hernandez A, Nussenzweig A, Mirkin SM.
Hisey JA, et al. Among authors: rastokina a.
Nucleic Acids Res. 2024 May 8;52(8):4361-4374. doi: 10.1093/nar/gkae124.
Nucleic Acids Res. 2024.
PMID: 38381906
Free PMC article.
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Pathogenic CANVAS (AAGGG)n repeats stall DNA replication due to the formation of alternative DNA structures.
Hisey JA, Radchenko EA, Ceschi S, Rastokina A, Mandel NH, McGinty RJ, Matos-Rodrigues G, Hernandez A, Nussenzweig A, Mirkin SM.
Hisey JA, et al. Among authors: rastokina a.
bioRxiv [Preprint]. 2023 Jul 26:2023.07.25.550509. doi: 10.1101/2023.07.25.550509.
bioRxiv. 2023.
PMID: 37546920
Free PMC article.
Updated.
Preprint.
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