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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2004 1
2005 1
2006 1
2007 2
2008 2
2009 1
2010 3
2011 3
2012 2
2013 1
2014 1
2015 6
2016 7
2017 7
2018 3
2019 1
2020 6
2021 7
2022 3
2023 7
2024 0

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56 results

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Page 1
Discovery of 5-{4-[(7-Ethyl-6-oxo-5,6-dihydro-1,5-naphthyridin-3-yl)methyl]piperazin-1-yl}-N-methylpyridine-2-carboxamide (AZD5305): A PARP1-DNA Trapper with High Selectivity for PARP1 over PARP2 and Other PARPs.
Johannes JW, Balazs A, Barratt D, Bista M, Chuba MD, Cosulich S, Critchlow SE, Degorce SL, Di Fruscia P, Edmondson SD, Embrey K, Fawell S, Ghosh A, Gill SJ, Gunnarsson A, Hande SM, Heightman TD, Hemsley P, Illuzzi G, Lane J, Larner C, Leo E, Liu L, Madin A, Martin S, McWilliams L, O'Connor MJ, Orme JP, Pachl F, Packer MJ, Pei X, Pike A, Schimpl M, She H, Staniszewska AD, Talbot V, Underwood E, Varnes JG, Xue L, Yao T, Zhang K, Zhang AX, Zheng X. Johannes JW, et al. Among authors: gunnarsson a. J Med Chem. 2021 Oct 14;64(19):14498-14512. doi: 10.1021/acs.jmedchem.1c01012. Epub 2021 Sep 27. J Med Chem. 2021. PMID: 34570508
Quantification of protein cargo loading into engineered extracellular vesicles at single-vesicle and single-molecule resolution.
Silva AM, Lázaro-Ibáñez E, Gunnarsson A, Dhande A, Daaboul G, Peacock B, Osteikoetxea X, Salmond N, Friis KP, Shatnyeva O, Dekker N. Silva AM, et al. Among authors: gunnarsson a. J Extracell Vesicles. 2021 Aug;10(10):e12130. doi: 10.1002/jev2.12130. Epub 2021 Aug 2. J Extracell Vesicles. 2021. PMID: 34377376 Free PMC article.
Compounds activating VCP D1 ATPase enhance both autophagic and proteasomal neurotoxic protein clearance.
Wrobel L, Hill SM, Djajadikerta A, Fernandez-Estevez M, Karabiyik C, Ashkenazi A, Barratt VJ, Stamatakou E, Gunnarsson A, Rasmusson T, Miele EW, Beaton N, Bruderer R, Feng Y, Reiter L, Castaldi MP, Jarvis R, Tan K, Bürli RW, Rubinsztein DC. Wrobel L, et al. Among authors: gunnarsson a. Nat Commun. 2022 Jul 16;13(1):4146. doi: 10.1038/s41467-022-31905-0. Nat Commun. 2022. PMID: 35842429 Free PMC article.
TOP-EVs: Technology of Protein delivery through Extracellular Vesicles is a versatile platform for intracellular protein delivery.
Ilahibaks NF, Ardisasmita AI, Xie S, Gunnarsson A, Brealey J, Vader P, de Jong OG, de Jager S, Dekker N, Peacock B, Schiffelers RM, Sluijter JPG, Lei Z. Ilahibaks NF, et al. Among authors: gunnarsson a. J Control Release. 2023 Mar;355:579-592. doi: 10.1016/j.jconrel.2023.02.003. Epub 2023 Feb 15. J Control Release. 2023. PMID: 36746337 Free article.
Creating Designer Engineered Extracellular Vesicles for Diverse Ligand Display, Target Recognition, and Controlled Protein Loading and Delivery.
Ivanova A, Badertscher L, O'Driscoll G, Bergman J, Gordon E, Gunnarsson A, Johansson C, Munson MJ, Spinelli C, Torstensson S, Vilén L, Voirel A, Wiseman J, Rak J, Dekker N, Lázaro-Ibáñez E. Ivanova A, et al. Among authors: gunnarsson a. Adv Sci (Weinh). 2023 Dec;10(34):e2304389. doi: 10.1002/advs.202304389. Epub 2023 Oct 22. Adv Sci (Weinh). 2023. PMID: 37867228 Free PMC article.
Quaternary glucocorticoid receptor structure highlights allosteric interdomain communication.
Postel S, Wissler L, Johansson CA, Gunnarsson A, Gordon E, Collins B, Castaldo M, Köhler C, Öling D, Johansson P, Fröderberg Roth L, Beinsteiner B, Dainty I, Delaney S, Klaholz BP, Billas IML, Edman K. Postel S, et al. Among authors: gunnarsson a. Nat Struct Mol Biol. 2023 Mar;30(3):286-295. doi: 10.1038/s41594-022-00914-4. Epub 2023 Feb 6. Nat Struct Mol Biol. 2023. PMID: 36747092
Designing Selective Drug-like Molecular Glues for the Glucocorticoid Receptor/14-3-3 Protein-Protein Interaction.
Pallesen JS, Munier CC, Bosica F, Andrei SA, Edman K, Gunnarsson A, La Sala G, Putra OD, Srdanović S, Wilson AJ, Wissler L, Ottmann C, Perry MWD, O'Mahony G. Pallesen JS, et al. Among authors: gunnarsson a. J Med Chem. 2022 Dec 22;65(24):16818-16828. doi: 10.1021/acs.jmedchem.2c01635. Epub 2022 Dec 9. J Med Chem. 2022. PMID: 36484727 Free PMC article.
A cell-active cyclic peptide targeting the Nrf2/Keap1 protein-protein interaction.
Iegre J, Krajcovicova S, Gunnarsson A, Wissler L, Käck H, Luchniak A, Tångefjord S, Narjes F, Spring DR. Iegre J, et al. Among authors: gunnarsson a. Chem Sci. 2023 Sep 20;14(39):10800-10805. doi: 10.1039/d3sc04083f. eCollection 2023 Oct 11. Chem Sci. 2023. PMID: 37829032 Free PMC article.
56 results