Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

153 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Results By Year timeline is not available.
Page 1
Substrate specificity and novel selective inhibitors of TNF-alpha converting enzyme (TACE) from two-dimensional substrate mapping.
Lambert MH, Blackburn RK, Seaton TD, Kassel DB, Kinder DS, Leesnitzer MA, Bickett DM, Warner JR, Andersen MW, Badiang JG, Cowan DJ, Gaul MD, Petrov KG, Rabinowitz MH, Wiethe RW, Becherer JD, McDougald DL, Musso DL, Andrews RC, Moss ML. Lambert MH, et al. Among authors: andrews rc. Comb Chem High Throughput Screen. 2005 Jun;8(4):327-39. doi: 10.2174/1386207054020840. Comb Chem High Throughput Screen. 2005. PMID: 16101009
Inhibition of tumor necrosis factor-alpha (TNF-alpha) production and arthritis in the rat by GW3333, a dual inhibitor of TNF-alpha-converting enzyme and matrix metalloproteinases.
Conway JG, Andrews RC, Beaudet B, Bickett DM, Boncek V, Brodie TA, Clark RL, Crumrine RC, Leenitzer MA, McDougald DL, Han B, Hedeen K, Lin P, Milla M, Moss M, Pink H, Rabinowitz MH, Tippin T, Scates PW, Selph J, Stimpson SA, Warner J, Becherer JD. Conway JG, et al. Among authors: andrews rc. J Pharmacol Exp Ther. 2001 Sep;298(3):900-8. J Pharmacol Exp Ther. 2001. PMID: 11504783
N-hydroxyformamide peptidomimetics as TACE/matrix metalloprotease inhibitors: oral activity via P1' isobutyl substitution.
Musso DL, Andersen MW, Andrews RC, Austin R, Beaudet EJ, Becherer JD, Bubacz DG, Bickett DM, Chan JH, Conway JG, Cowan DJ, Gaul MD, Glennon KC, Hedeen KM, Lambert MH, Leesnitzer MA, McDougald DL, Mitchell JL, Moss ML, Rabinowitz MH, Rizzolio MC, Schaller LT, Stanford JB, Tippin T, Warner JR, Whitesell LG, Wiethe RW. Musso DL, et al. Among authors: andrews rc. Bioorg Med Chem Lett. 2001 Aug 20;11(16):2147-51. doi: 10.1016/s0960-894x(01)00377-8. Bioorg Med Chem Lett. 2001. PMID: 11514157
CYP3A induction by N-hydroxyformamide tumor necrosis factor-alpha converting enzyme/matrix metalloproteinase inhibitors use of a pregname X receptor activation assay and primary hepatocyte culture for assessing induction potential in humans.
Tippin TK, Hamilton G, Moore L, Beaudet EJ, Jolley S, Brodie TA, Andrews RC, Becherer JD, McDougald DL, Gaul MD, Hoivik DJ, Mellon-Kusibab K, Lehmann J, Kliewer S, Novick S, Laethem R, Zhao Z, LeCluyse EL. Tippin TK, et al. Among authors: andrews rc. Drug Metab Dispos. 2003 Jul;31(7):870-7. doi: 10.1124/dmd.31.7.870. Drug Metab Dispos. 2003. PMID: 12814963
TACE and other ADAM proteases as targets for drug discovery.
Moss ML, White JM, Lambert MH, Andrews RC. Moss ML, et al. Among authors: andrews rc. Drug Discov Today. 2001 Apr 1;6(8):417-426. doi: 10.1016/s1359-6446(01)01738-x. Drug Discov Today. 2001. PMID: 11301286
Metalloproteinase inhibitors for the disintegrin-like metalloproteinases ADAM10 and ADAM17 that differentially block constitutive and phorbol ester-inducible shedding of cell surface molecules.
Ludwig A, Hundhausen C, Lambert MH, Broadway N, Andrews RC, Bickett DM, Leesnitzer MA, Becherer JD. Ludwig A, et al. Among authors: andrews rc. Comb Chem High Throughput Screen. 2005 Mar;8(2):161-71. doi: 10.2174/1386207053258488. Comb Chem High Throughput Screen. 2005. PMID: 15777180 Review.
6-Azasteroids: structure-activity relationships for inhibition of type 1 and 2 human 5 alpha-reductase and human adrenal 3 beta-hydroxy-delta 5-steroid dehydrogenase/3-keto-delta 5-steroid isomerase.
Frye SV, Haffner CD, Maloney PR, Mook RA Jr, Dorsey GF Jr, Hiner RN, Cribbs CM, Wheeler TN, Ray JA, Andrews RC, et al. Frye SV, et al. Among authors: andrews rc. J Med Chem. 1994 Jul 22;37(15):2352-60. doi: 10.1021/jm00041a014. J Med Chem. 1994. PMID: 8057283
Discovery of bioavailable inhibitors of secretory phospholipase A2.
Blanchard SG, Andrews RC, Brown PJ, Gan LS, Lee FW, Sinhababu AK, Wheeler TN. Blanchard SG, et al. Among authors: andrews rc. Pharm Biotechnol. 1998;11:445-63. doi: 10.1007/0-306-47384-4_19. Pharm Biotechnol. 1998. PMID: 9760691 Review.
153 results