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2017 1
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2021 5
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2023 6
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Page 1
Single-cell CRISPR screens in vivo map T cell fate regulomes in cancer.
Zhou P, Shi H, Huang H, Sun X, Yuan S, Chapman NM, Connelly JP, Lim SA, Saravia J, Kc A, Pruett-Miller SM, Chi H. Zhou P, et al. Among authors: kc a. Nature. 2023 Dec;624(7990):154-163. doi: 10.1038/s41586-023-06733-x. Epub 2023 Nov 15. Nature. 2023. PMID: 37968405 Free PMC article.
Targeting REGNASE-1 programs long-lived effector T cells for cancer therapy.
Wei J, Long L, Zheng W, Dhungana Y, Lim SA, Guy C, Wang Y, Wang YD, Qian C, Xu B, Kc A, Saravia J, Huang H, Yu J, Doench JG, Geiger TL, Chi H. Wei J, et al. Among authors: kc a. Nature. 2019 Dec;576(7787):471-476. doi: 10.1038/s41586-019-1821-z. Epub 2019 Dec 11. Nature. 2019. PMID: 31827283 Free PMC article.
CXCR6 orchestrates brain CD8+ T cell residency and limits mouse Alzheimer's disease pathology.
Su W, Saravia J, Risch I, Rankin S, Guy C, Chapman NM, Shi H, Sun Y, Kc A, Li W, Huang H, Lim SA, Hu H, Wang Y, Liu D, Jiao Y, Chen PC, Soliman H, Yan KK, Zhang J, Vogel P, Liu X, Serrano GE, Beach TG, Yu J, Peng J, Chi H. Su W, et al. Among authors: kc a. Nat Immunol. 2023 Oct;24(10):1735-1747. doi: 10.1038/s41590-023-01604-z. Epub 2023 Sep 7. Nat Immunol. 2023. PMID: 37679549
CRISPR screens unveil signal hubs for nutrient licensing of T cell immunity.
Long L, Wei J, Lim SA, Raynor JL, Shi H, Connelly JP, Wang H, Guy C, Xie B, Chapman NM, Fu G, Wang Y, Huang H, Su W, Saravia J, Risch I, Wang YD, Li Y, Niu M, Dhungana Y, Kc A, Zhou P, Vogel P, Yu J, Pruett-Miller SM, Peng J, Chi H. Long L, et al. Among authors: kc a. Nature. 2021 Dec;600(7888):308-313. doi: 10.1038/s41586-021-04109-7. Epub 2021 Nov 18. Nature. 2021. PMID: 34795452 Free PMC article.
Metabolic control of TFH cells and humoral immunity by phosphatidylethanolamine.
Fu G, Guy CS, Chapman NM, Palacios G, Wei J, Zhou P, Long L, Wang YD, Qian C, Dhungana Y, Huang H, Kc A, Shi H, Rankin S, Brown SA, Johnson A, Wakefield R, Robinson CG, Liu X, Sheyn A, Yu J, Jackowski S, Chi H. Fu G, et al. Among authors: kc a. Nature. 2021 Jul;595(7869):724-729. doi: 10.1038/s41586-021-03692-z. Epub 2021 Jul 7. Nature. 2021. PMID: 34234346 Free PMC article.
PTEN directs developmental and metabolic signaling for innate-like T cell fate and tissue homeostasis.
Blanco DB, Chapman NM, Raynor JL, Xu C, Su W, Kc A, Li W, Lim SA, Schattgen S, Shi H, Risch I, Sun Y, Dhungana Y, Kim Y, Wei J, Rankin S, Neale G, Thomas PG, Yang K, Chi H. Blanco DB, et al. Among authors: kc a. Nat Cell Biol. 2022 Nov;24(11):1642-1654. doi: 10.1038/s41556-022-01011-w. Epub 2022 Oct 27. Nat Cell Biol. 2022. PMID: 36302969 Free PMC article.
The Hidden Threat: Endocrine Disruptors and Their Impact on Insulin Resistance.
Dagar M, Kumari P, Mirza AMW, Singh S, Ain NU, Munir Z, Javed T, Virk MFI, Javed S, Qizilbash FH, Kc A, Ekhator C, Bellegarde SB. Dagar M, et al. Among authors: kc a. Cureus. 2023 Oct 18;15(10):e47282. doi: 10.7759/cureus.47282. eCollection 2023 Oct. Cureus. 2023. PMID: 38021644 Free PMC article. Review.
Modular chimeric cytokine receptors with leucine zippers enhance the antitumour activity of CAR T cells via JAK/STAT signalling.
Bell M, Lange S, Sejdiu BI, Ibanez J, Shi H, Sun X, Meng X, Nguyen P, Sutton M, Wagner J, Kc A, Langfitt D, Patil SL, Tan H, Pandey RV, Li Y, Yuan ZF, Anido AA, Ho M, Sheppard H, Vogel P, Yu J, Peng J, Chi H, Babu MM, Krenciute G, Gottschalk S. Bell M, et al. Among authors: kc a. Nat Biomed Eng. 2023 Nov 30. doi: 10.1038/s41551-023-01143-w. Online ahead of print. Nat Biomed Eng. 2023. PMID: 38036617
23 results