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2020 | 3 |
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Page 1
The Zinc-Sensing Receptor GPR39 in Physiology and as a Pharmacological Target.
Int J Mol Sci. 2021 Apr 8;22(8):3872. doi: 10.3390/ijms22083872.
Int J Mol Sci. 2021.
PMID: 33918078
Free PMC article.
Review.
Activation of the hypoxia response pathway protects against age-induced cardiac hypertrophy.
Röning T, Magga J, Laitakari A, Halmetoja R, Tapio J, Dimova EY, Szabo Z, Rahtu-Korpela L, Kemppi A, Walkinshaw G, Myllyharju J, Kerkelä R, Koivunen P, Serpi R.
Röning T, et al. Among authors: laitakari a.
J Mol Cell Cardiol. 2022 Mar;164:148-155. doi: 10.1016/j.yjmcc.2021.12.003. Epub 2021 Dec 14.
J Mol Cell Cardiol. 2022.
PMID: 34919895
Free article.
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Activation of the hypoxia response protects mice from amyloid-β accumulation.
Ollonen T, Kurkela M, Laitakari A, Sakko S, Koivisto H, Myllyharju J, Tanila H, Serpi R, Koivunen P.
Ollonen T, et al. Among authors: laitakari a.
Cell Mol Life Sci. 2022 Jul 19;79(8):432. doi: 10.1007/s00018-022-04460-6.
Cell Mol Life Sci. 2022.
PMID: 35852609
Free PMC article.
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HIF-P4H-2 inhibition enhances intestinal fructose metabolism and induces thermogenesis protecting against NAFLD.
Laitakari A, Tapio J, Mäkelä KA, Herzig KH, Dengler F, Gylling H, Walkinshaw G, Myllyharju J, Dimova EY, Serpi R, Koivunen P.
Laitakari A, et al.
J Mol Med (Berl). 2020 May;98(5):719-731. doi: 10.1007/s00109-020-01903-0. Epub 2020 Apr 15.
J Mol Med (Berl). 2020.
PMID: 32296880
Free PMC article.
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The Amino-Terminal Oligomerization Domain of Angiopoietin-2 Affects Vascular Remodeling, Mammary Gland Tumor Growth, and Lung Metastasis in Mice.
Kapiainen E, Kihlström MK, Pietilä R, Kaakinen M, Ronkainen VP, Tu H, Heikkinen A, Devarajan R, Miinalainen I, Laitakari A, Ansarizadeh M, Zhang Q, Wei GH, Ruddock L, Pihlajaniemi T, Elamaa H, Eklund L.
Kapiainen E, et al. Among authors: laitakari a.
Cancer Res. 2021 Jan 1;81(1):129-143. doi: 10.1158/0008-5472.CAN-19-1904. Epub 2020 Oct 9.
Cancer Res. 2021.
PMID: 33037065
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Systemic inactivation of hypoxia-inducible factor prolyl 4-hydroxylase 2 in mice protects from alcohol-induced fatty liver disease.
Laitakari A, Ollonen T, Kietzmann T, Walkinshaw G, Mennerich D, Izzi V, Haapasaari KM, Myllyharju J, Serpi R, Dimova EY, Koivunen P.
Laitakari A, et al.
Redox Biol. 2019 Apr;22:101145. doi: 10.1016/j.redox.2019.101145. Epub 2019 Feb 19.
Redox Biol. 2019.
PMID: 30802717
Free PMC article.
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Systemic long-term inactivation of hypoxia-inducible factor prolyl 4-hydroxylase 2 ameliorates aging-induced changes in mice without affecting their life span.
Laitakari A, Huttunen R, Kuvaja P, Hannuksela P, Szabo Z, Heikkilä M, Kerkelä R, Myllyharju J, Dimova EY, Serpi R, Koivunen P.
Laitakari A, et al.
FASEB J. 2020 Apr;34(4):5590-5609. doi: 10.1096/fj.201902331R. Epub 2020 Feb 25.
FASEB J. 2020.
PMID: 32100354
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