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The ontogeny of drug metabolizing enzymes and transporters in the rat.
de Zwart L, Scholten M, Monbaliu JG, Annaert PP, Van Houdt JM, Van den Wyngaert I, De Schaepdrijver LM, Bailey GP, Coogan TP, Coussement WC, Mannens GS. de Zwart L, et al. Among authors: annaert pp. Reprod Toxicol. 2008 Nov-Dec;26(3-4):220-30. doi: 10.1016/j.reprotox.2008.09.010. Epub 2008 Oct 7. Reprod Toxicol. 2008. PMID: 18926897
Physiologically Based Pharmacokinetic Predictions of Tramadol Exposure Throughout Pediatric Life: an Analysis of the Different Clearance Contributors with Emphasis on CYP2D6 Maturation.
T'jollyn H, Snoeys J, Vermeulen A, Michelet R, Cuyckens F, Mannens G, Van Peer A, Annaert P, Allegaert K, Van Bocxlaer J, Boussery K. T'jollyn H, et al. AAPS J. 2015 Nov;17(6):1376-87. doi: 10.1208/s12248-015-9803-z. Epub 2015 Jul 25. AAPS J. 2015. PMID: 26209290 Free PMC article.
Lipophilic nalmefene prodrugs to achieve a one-month sustained release.
Gaekens T, Guillaume M, Borghys H, De Zwart LL, de Vries R, Embrechts RC, Vermeulen A, Megens AA, Leysen JE, Herdewijn P, Annaert PP, Atack JR. Gaekens T, et al. Among authors: annaert pp. J Control Release. 2016 Jun 28;232:196-202. doi: 10.1016/j.jconrel.2016.04.029. Epub 2016 Apr 21. J Control Release. 2016. PMID: 27107723
Strategies for Determining Correct Cytochrome P450 Contributions in Hepatic Clearance Predictions: In Vitro-In Vivo Extrapolation as Modelling Approach and Tramadol as Proof-of Concept Compound.
T'jollyn H, Snoeys J, Van Bocxlaer J, De Bock L, Annaert P, Van Peer A, Allegaert K, Mannens G, Vermeulen A, Boussery K. T'jollyn H, et al. Eur J Drug Metab Pharmacokinet. 2017 Jun;42(3):537-543. doi: 10.1007/s13318-016-0355-0. Eur J Drug Metab Pharmacokinet. 2017. PMID: 27317395
193 results