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Page 1
Mistimed origin licensing and activation stabilize common fragile sites under tight DNA-replication checkpoint activation.
Brison O, Gnan S, Azar D, Koundrioukoff S, Melendez-Garcia R, Kim SJ, Schmidt M, El-Hilali S, Jaszczyszyn Y, Lachages AM, Thermes C, Chen CL, Debatisse M. Brison O, et al. Among authors: lachages am. Nat Struct Mol Biol. 2023 Apr;30(4):539-550. doi: 10.1038/s41594-023-00949-1. Epub 2023 Apr 6. Nat Struct Mol Biol. 2023. PMID: 37024657
Spheroplexes: Hybrid PLGA-cationic lipid nanoparticles, for in vitro and oral delivery of siRNA.
Arruda DC, Lachagès AM, Demory H, Escriou G, Lai-Kuen R, Dugas PY, Hoffmann C, Bessoles S, Sarrabayrouse G, Malachias A, Finet S, Gastelois PL, de Almeida Macedo WA, da Silva Cunha A Jr, Bigey P, Escriou V. Arruda DC, et al. Among authors: lachages am. J Control Release. 2022 Oct;350:228-243. doi: 10.1016/j.jconrel.2022.08.030. Epub 2022 Aug 24. J Control Release. 2022. PMID: 35995297 Free article.
Hepatic stellate cell hypertrophy is associated with metabolic liver fibrosis.
Hoffmann C, Djerir NEH, Danckaert A, Fernandes J, Roux P, Charrueau C, Lachagès AM, Charlotte F, Brocheriou I, Clément K, Aron-Wisnewsky J, Foufelle F, Ratziu V, Hainque B, Bonnefont-Rousselot D, Bigey P, Escriou V. Hoffmann C, et al. Among authors: lachages am. Sci Rep. 2020 Mar 2;10(1):3850. doi: 10.1038/s41598-020-60615-0. Sci Rep. 2020. PMID: 32123215 Free PMC article.
Molecular profiling of common fragile sites in human fibroblasts.
Le Tallec B, Dutrillaux B, Lachages AM, Millot GA, Brison O, Debatisse M. Le Tallec B, et al. Among authors: lachages am. Nat Struct Mol Biol. 2011 Nov 6;18(12):1421-3. doi: 10.1038/nsmb.2155. Nat Struct Mol Biol. 2011. PMID: 22056772