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NLRP3 licenses NLRP11 for inflammasome activation in human macrophages.
Gangopadhyay A, Devi S, Tenguria S, Carriere J, Nguyen H, Jäger E, Khatri H, Chu LH, Ratsimandresy RA, Dorfleutner A, Stehlik C. Gangopadhyay A, et al. Nat Immunol. 2022 Jun;23(6):892-903. doi: 10.1038/s41590-022-01220-3. Epub 2022 May 27. Nat Immunol. 2022. PMID: 35624206 Free PMC article.
The PYRIN domain-only protein POP2 inhibits inflammasome priming and activation.
Ratsimandresy RA, Chu LH, Khare S, de Almeida L, Gangopadhyay A, Indramohan M, Misharin AV, Greaves DR, Perlman H, Dorfleutner A, Stehlik C. Ratsimandresy RA, et al. Among authors: gangopadhyay a. Nat Commun. 2017 Jun 5;8:15556. doi: 10.1038/ncomms15556. Nat Commun. 2017. PMID: 28580931 Free PMC article.
The PYRIN domain-only protein POP3 inhibits ALR inflammasomes and regulates responses to infection with DNA viruses.
Khare S, Ratsimandresy RA, de Almeida L, Cuda CM, Rellick SL, Misharin AV, Wallin MC, Gangopadhyay A, Forte E, Gottwein E, Perlman H, Reed JC, Greaves DR, Dorfleutner A, Stehlik C. Khare S, et al. Among authors: gangopadhyay a. Nat Immunol. 2014 Apr;15(4):343-53. doi: 10.1038/ni.2829. Epub 2014 Feb 16. Nat Immunol. 2014. PMID: 24531343 Free PMC article.