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Year Number of Results
2013 1
2014 2
2015 1
2016 4
2017 1
2018 2
2021 3
2023 1
2024 0

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14 results

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Page 1
Tuning sterol extraction kinetics yields a renal-sparing polyene antifungal.
Maji A, Soutar CP, Zhang J, Lewandowska A, Uno BE, Yan S, Shelke Y, Murhade G, Nimerovsky E, Borcik CG, Arango AS, Lange JD, Marin-Toledo JP, Lyu Y, Bailey KL, Roady PJ, Holler JT, Khandelwal A, SantaMaria AM, Sanchez H, Juvvadi PR, Johns G, Hageman MJ, Krise J, Gebremariam T, Youssef EG, Bartizal K, Marr KA, Steinbach WJ, Ibrahim AS, Patterson TF, Wiederhold NP, Andes DR, Pogorelov TV, Schwieters CD, Fan TM, Rienstra CM, Burke MD. Maji A, et al. Among authors: khandelwal a. Nature. 2023 Nov;623(7989):1079-1085. doi: 10.1038/s41586-023-06710-4. Epub 2023 Nov 8. Nature. 2023. PMID: 37938782 Free PMC article.
Resorcinol-Based Grp94-Selective Inhibitors.
Khandelwal A, Crowley VM, Blagg BSJ. Khandelwal A, et al. ACS Med Chem Lett. 2017 Sep 1;8(10):1013-1018. doi: 10.1021/acsmedchemlett.7b00193. eCollection 2017 Oct 12. ACS Med Chem Lett. 2017. PMID: 29057043 Free PMC article.
Selective Inhibition of the Hsp90α Isoform.
Mishra SJ, Khandelwal A, Banerjee M, Balch M, Peng S, Davis RE, Merfeld T, Munthali V, Deng J, Matts RL, Blagg BSJ. Mishra SJ, et al. Among authors: khandelwal a. Angew Chem Int Ed Engl. 2021 May 3;60(19):10547-10551. doi: 10.1002/anie.202015422. Epub 2021 Mar 26. Angew Chem Int Ed Engl. 2021. PMID: 33621416 Free PMC article.
Structure-guided design of an Hsp90β N-terminal isoform-selective inhibitor.
Khandelwal A, Kent CN, Balch M, Peng S, Mishra SJ, Deng J, Day VW, Liu W, Subramanian C, Cohen M, Holzbeierlein JM, Matts R, Blagg BSJ. Khandelwal A, et al. Nat Commun. 2018 Jan 30;9(1):425. doi: 10.1038/s41467-017-02013-1. Nat Commun. 2018. PMID: 29382832 Free PMC article.
Development of radamide analogs as Grp94 inhibitors.
Muth A, Crowley V, Khandelwal A, Mishra S, Zhao J, Hall J, Blagg BS. Muth A, et al. Among authors: khandelwal a. Bioorg Med Chem. 2014 Aug 1;22(15):4083-98. doi: 10.1016/j.bmc.2014.05.075. Epub 2014 Jun 12. Bioorg Med Chem. 2014. PMID: 25027801 Free PMC article.
Fungicidal amphotericin B sponges are assemblies of staggered asymmetric homodimers encasing large void volumes.
Lewandowska A, Soutar CP, Greenwood AI, Nimerovsky E, De Lio AM, Holler JT, Hisao GS, Khandelwal A, Zhang J, SantaMaria AM, Schwieters CD, Pogorelov TV, Burke MD, Rienstra CM. Lewandowska A, et al. Among authors: khandelwal a. Nat Struct Mol Biol. 2021 Dec;28(12):972-981. doi: 10.1038/s41594-021-00685-4. Epub 2021 Dec 9. Nat Struct Mol Biol. 2021. PMID: 34887566 Free PMC article.
14 results