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Single-cell profiling of peripheral neuroblastic tumors identifies an aggressive transitional state that bridges an adrenergic-mesenchymal trajectory.
Cell Rep. 2022 Oct 4;41(1):111455. doi: 10.1016/j.celrep.2022.111455.
Cell Rep. 2022.
PMID: 36198269
Free article.
Loss of stress sensor GADD45A promotes stem cell activity and ferroptosis resistance in LGR4/HOXA9-dependent AML.
Hassan N, Yi H, Malik B, Gaspard-Boulinc LC, Samaraweera SEE, Casolari DA, Seneviratne JA, Balachandran A, Chew T, Duly A, Carter DRR, Cheung B, Norris M, Haber M, Kavallaris M, Marshall GM, Zhang XD, Liu T, Wang J, Liebermann DA, D'Andrea RJJ, Wang JY.
Hassan N, et al. Among authors: balachandran a.
Blood. 2024 Apr 5:blood.2024024072. doi: 10.1182/blood.2024024072. Online ahead of print.
Blood. 2024.
PMID: 38579286
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Oncogenic cooperation between TCF7-SPI1 and NRAS(G12D) requires β-catenin activity to drive T-cell acute lymphoblastic leukemia.
Van Thillo Q, De Bie J, Seneviratne JA, Demeyer S, Omari S, Balachandran A, Zhai V, Tam WL, Sweron B, Geerdens E, Gielen O, Provost S, Segers H, Boeckx N, Marshall GM, Cheung BB, Isobe K, Kato I, Takita J, Amos TG, Deveson IW, McCalmont H, Lock RB, Oxley EP, Garwood MM, Dickins RA, Uyttebroeck A, Carter DR, Cools J, de Bock CE.
Van Thillo Q, et al. Among authors: balachandran a.
Nat Commun. 2021 Jul 6;12(1):4164. doi: 10.1038/s41467-021-24442-9.
Nat Commun. 2021.
PMID: 34230493
Free PMC article.
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Mitotic Dysregulation at Tumor Initiation Creates a Therapeutic Vulnerability to Combination Anti-Mitotic and Pro-Apoptotic Agents for MYCN-Driven Neuroblastoma.
Zhai L, Balachandran A, Larkin R, Seneviratne JA, Chung SA, Lalwani A, Tsubota S, Beck D, Kadomatsu K, Beckers A, Durink K, De Preter K, Speleman F, Haber M, Norris MD, Swarbrick A, Cheung BB, Marshall GM, Carter DR.
Zhai L, et al. Among authors: balachandran a.
Int J Mol Sci. 2023 Oct 25;24(21):15571. doi: 10.3390/ijms242115571.
Int J Mol Sci. 2023.
PMID: 37958555
Free PMC article.
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Complement C5aR1 Signaling Promotes Polarization and Proliferation of Embryonic Neural Progenitor Cells through PKCζ.
Coulthard LG, Hawksworth OA, Li R, Balachandran A, Lee JD, Sepehrband F, Kurniawan N, Jeanes A, Simmons DG, Wolvetang E, Woodruff TM.
Coulthard LG, et al. Among authors: balachandran a.
J Neurosci. 2017 May 31;37(22):5395-5407. doi: 10.1523/JNEUROSCI.0525-17.2017. Epub 2017 Apr 28.
J Neurosci. 2017.
PMID: 28455369
Free PMC article.
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Proteomics of Huntington's disease-affected human embryonic stem cells reveals an evolving pathology involving mitochondrial dysfunction and metabolic disturbances.
McQuade LR, Balachandran A, Scott HA, Khaira S, Baker MS, Schmidt U.
McQuade LR, et al. Among authors: balachandran a.
J Proteome Res. 2014 Dec 5;13(12):5648-59. doi: 10.1021/pr500649m. Epub 2014 Oct 31.
J Proteome Res. 2014.
PMID: 25316320
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