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Targeting immunosuppressive Ly6C+ classical monocytes reverses anti-PD-1/CTLA-4 immunotherapy resistance.
Rodriguez BL, Chen L, Li Y, Miao S, Peng DH, Fradette JJ, Diao L, Konen JM, Alvarez FRR, Solis LM, Yi X, Padhye A, Gibson LA, Ochieng JK, Zhou X, Wang J, Gibbons DL. Rodriguez BL, et al. Among authors: padhye a. Front Immunol. 2023 Jun 28;14:1161869. doi: 10.3389/fimmu.2023.1161869. eCollection 2023. Front Immunol. 2023. PMID: 37449205 Free PMC article.
A potent antibiotic-loaded bone-cement implant against staphylococcal bone infections.
Ghosh S, Sinha M, Samanta R, Sadhasivam S, Bhattacharyya A, Nandy A, Saini S, Tandon N, Singh H, Gupta S, Chauhan A, Aavula KK, Varghese SS, Shi P, Ghosh S, Garg MK, Saha T, Padhye A, Ghosh S, Jang HL, Sengupta S. Ghosh S, et al. Among authors: padhye a. Nat Biomed Eng. 2022 Oct;6(10):1180-1195. doi: 10.1038/s41551-022-00950-x. Epub 2022 Oct 13. Nat Biomed Eng. 2022. PMID: 36229662 Free PMC article.
Dual Inhibition of MEK and AXL Targets Tumor Cell Heterogeneity and Prevents Resistant Outgrowth Mediated by the Epithelial-to-Mesenchymal Transition in NSCLC.
Konen JM, Rodriguez BL, Padhye A, Ochieng JK, Gibson L, Diao L, Fowlkes NW, Fradette JJ, Peng DH, Cardnell RJ, Kovacs JJ, Wang J, Byers LA, Gibbons DL. Konen JM, et al. Among authors: padhye a. Cancer Res. 2021 Mar 1;81(5):1398-1412. doi: 10.1158/0008-5472.CAN-20-1895. Epub 2021 Jan 5. Cancer Res. 2021. PMID: 33402388 Free PMC article.