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Page 1
Tacrolimus- and sirolimus-induced human β cell dysfunction is reversible and preventable.
Dai C, Walker JT, Shostak A, Padgett A, Spears E, Wisniewski S, Poffenberger G, Aramandla R, Dean ED, Prasad N, Levy SE, Greiner DL, Shultz LD, Bottino R, Powers AC. Dai C, et al. Among authors: aramandla r. JCI Insight. 2020 Jan 16;5(1):e130770. doi: 10.1172/jci.insight.130770. JCI Insight. 2020. PMID: 31941840 Free PMC article.
Stress-impaired transcription factor expression and insulin secretion in transplanted human islets.
Dai C, Kayton NS, Shostak A, Poffenberger G, Cyphert HA, Aramandla R, Thompson C, Papagiannis IG, Emfinger C, Shiota M, Stafford JM, Greiner DL, Herrera PL, Shultz LD, Stein R, Powers AC. Dai C, et al. Among authors: aramandla r. J Clin Invest. 2016 May 2;126(5):1857-70. doi: 10.1172/JCI83657. Epub 2016 Apr 11. J Clin Invest. 2016. PMID: 27064285 Free PMC article.
Development of a reliable automated screening system to identify small molecules and biologics that promote human β-cell regeneration.
Aamodt KI, Aramandla R, Brown JJ, Fiaschi-Taesch N, Wang P, Stewart AF, Brissova M, Powers AC. Aamodt KI, et al. Among authors: aramandla r. Am J Physiol Endocrinol Metab. 2016 Nov 1;311(5):E859-E868. doi: 10.1152/ajpendo.00515.2015. Epub 2016 Sep 13. Am J Physiol Endocrinol Metab. 2016. PMID: 27624103 Free PMC article.
α Cell Function and Gene Expression Are Compromised in Type 1 Diabetes.
Brissova M, Haliyur R, Saunders D, Shrestha S, Dai C, Blodgett DM, Bottino R, Campbell-Thompson M, Aramandla R, Poffenberger G, Lindner J, Pan FC, von Herrath MG, Greiner DL, Shultz LD, Sanyoura M, Philipson LH, Atkinson M, Harlan DM, Levy SE, Prasad N, Stein R, Powers AC. Brissova M, et al. Among authors: aramandla r. Cell Rep. 2018 Mar 6;22(10):2667-2676. doi: 10.1016/j.celrep.2018.02.032. Cell Rep. 2018. PMID: 29514095 Free PMC article.
Cystic fibrosis-related diabetes is caused by islet loss and inflammation.
Hart NJ, Aramandla R, Poffenberger G, Fayolle C, Thames AH, Bautista A, Spigelman AF, Babon JAB, DeNicola ME, Dadi PK, Bush WS, Balamurugan AN, Brissova M, Dai C, Prasad N, Bottino R, Jacobson DA, Drumm ML, Kent SC, MacDonald PE, Powers AC. Hart NJ, et al. Among authors: aramandla r. JCI Insight. 2018 Apr 19;3(8):e98240. doi: 10.1172/jci.insight.98240. eCollection 2018 Apr 19. JCI Insight. 2018. PMID: 29669939 Free PMC article.
Ectonucleoside Triphosphate Diphosphohydrolase-3 Antibody Targets Adult Human Pancreatic β Cells for In Vitro and In Vivo Analysis.
Saunders DC, Brissova M, Phillips N, Shrestha S, Walker JT, Aramandla R, Poffenberger G, Flaherty DK, Weller KP, Pelletier J, Cooper T, Goff MT, Virostko J, Shostak A, Dean ED, Greiner DL, Shultz LD, Prasad N, Levy SE, Carnahan RH, Dai C, Sévigny J, Powers AC. Saunders DC, et al. Among authors: aramandla r. Cell Metab. 2019 Mar 5;29(3):745-754.e4. doi: 10.1016/j.cmet.2018.10.007. Epub 2018 Nov 15. Cell Metab. 2019. PMID: 30449685 Free PMC article.
Human islets expressing HNF1A variant have defective β cell transcriptional regulatory networks.
Haliyur R, Tong X, Sanyoura M, Shrestha S, Lindner J, Saunders DC, Aramandla R, Poffenberger G, Redick SD, Bottino R, Prasad N, Levy SE, Blind RD, Harlan DM, Philipson LH, Stein RW, Brissova M, Powers AC. Haliyur R, et al. Among authors: aramandla r. J Clin Invest. 2019 Jan 2;129(1):246-251. doi: 10.1172/JCI121994. Epub 2018 Dec 3. J Clin Invest. 2019. PMID: 30507613 Free PMC article.
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