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Post-translational remodeling of ryanodine receptor induces calcium leak leading to Alzheimer's disease-like pathologies and cognitive deficits.
Lacampagne A, Liu X, Reiken S, Bussiere R, Meli AC, Lauritzen I, Teich AF, Zalk R, Saint N, Arancio O, Bauer C, Duprat F, Briggs CA, Chakroborty S, Stutzmann GE, Shelanski ML, Checler F, Chami M, Marks AR. Lacampagne A, et al. Among authors: arancio o. Acta Neuropathol. 2017 Nov;134(5):749-767. doi: 10.1007/s00401-017-1733-7. Epub 2017 Jun 19. Acta Neuropathol. 2017. PMID: 28631094 Free article.
Tau is not necessary for amyloid-β-induced synaptic and memory impairments.
Puzzo D, Argyrousi EK, Staniszewski A, Zhang H, Calcagno E, Zuccarello E, Acquarone E, Fa' M, Li Puma DD, Grassi C, D'Adamio L, Kanaan NM, Fraser PE, Arancio O. Puzzo D, et al. Among authors: arancio o. J Clin Invest. 2020 Sep 1;130(9):4831-4844. doi: 10.1172/JCI137040. J Clin Invest. 2020. PMID: 32544084 Free PMC article.
206 results